Encontrados 3 documentos, a visualizar página 1 de 1
Intramolecular C–H insertion catalyzed by dirhodium(II) complexes using CO2 as ...
Zakrzewska, Malgorzata E.; Cal, Pedro M.S.D.; Candeias, Nuno R.; Bogel-Lukasik, R.; Afonso, Carlos A.M.; Ponte, Manuel Nunes; Gois, Pedro M.P.In this work, the intramolecular C–H insertion of diazoacetamides catalyzed by dirhodium(II) complexes and using CO2 as solvent is disclosed. The expected lactams were obtained in yields over 97%. The asymmetric intramolecular C–H insertion was also achieved and the β-lactam 14 was obtained in >97% yield and 65% ee using the chiral dirhodium(II) catalyst Rh2(S-PTTL)4. Finally, the dirhodium(II) complex Rh2(OAc)...
Geometry learning: The role of tasks, working models, and dynamic geometry soft...
Candeias, Nuno; Ponte, João Pedro daWe present several learning experiences that illustrate how three aspects of the geometric competence, constructing and analyzing properties of figures, identifying patterns and investigating and geometric problem solving, were developed by pupils that participated in the implementation of an innovative geometry teaching unit in grade 8. The topics addressed were dealing with properties of two dimensional figur...
Inserção C-H de carbenóides de ródio em água e reutilização do catalisador
Candeias,Nuno R.; Gois,Pedro M. P.; Afonso,Carlos A. M.A five-session laboratory experiment is described for the synthesis of a beta-lactam via Rh(II) catalysed intramolecular C-H insertion of a alpha-diazo-alpha-ethoxycarbonylacetamide. The metallo-carbene, responsible for the C-H bond activation, was generated from the diazo substrate and the catalyst Rh2(OAc)4. The high stability and solubility of the catalyst and the exclusive C-H insertion of the Rh-carbene al...
| Financiadores do RCAAP | |||||||
|
|
|
|
|
|
||