Encontrados 17 documentos, a visualizar página 1 de 2
Avaliação farmacológica e toxicológica do óleo essencial e extrato aquoso deLav...
Arantes, Silvia; Candeias, M. Fátima; Pereira, Marízia; Lopes, Orlando; Lima, Mónica; Cruz Morais, Júlio; Martins, M. RosárioAs plantas do género Lavandula L. pertencentes à família Labiatae, são plantas aromáticas de grande importância económica muito usadas na medicina tradicional. Neste estudo, foi selecionada uma espécie natural do Alentejo, Lavandula stoechas L. subsps. luisieri (Rozeira) Rozeira, vulgarmente conhecida por rosmaninho, recolhida de uma mancha da Herdade da Mitra (Évora) O objetivo deste estudo foi avaliar as ati...
Toxicological and pharmacological evaluation of the essential oil and aqueous e...
Arantes, Silvia; Candeias, M. Fátima; Pereira, Marizia; Lopes, Orlando; Lima, Mónica; Martins, M. RosárioLavenders belong to the family Labiatae and represent some of the most popular medicinal plants extensively used in aromatherapy. In this study, we selected Lavandula stoechas L. subsp. luisieri (Rozeira) Rozeira, endemic of Portugal, collected in Évora (Alentejo). The aim of this study was to evaluate the acute toxicity and the analgesic and anti-inflammatory activities of the essential oil and aqueous extrac...
Toxicological evaluation and hepatoprotective effect of Amanita ponderosa
Salvador, Cátia; Nunes, Patricia; Carvalho, Ana; Candeias, M. Fátima; Martins, M. Rosário; Caldeira, A. TeresaEdible mushrooms, moreover to their gastronomic characteristics, are a source of valuable nutrients and bioactive compounds with potential beneficial effects on human health. Currently mushrooms become attractive as functional foods due to medicinal properties and useful in preventing diseases shown antitumour and immunomodulating properties, cardioprotective, hepatoprotective, antibacterial, antiviral and anti...
Culturas de fungos basidiomicetos em resíduos agroindustriais para produção de ...
Salvador, C; Candeias, M F; Martins, M Rosário; Caldeira, A TeresaSeveral agro-industrial residues (beet wastes, tomato pomace, sunflower straw, wheat straw and rice peel) were used to develop liquid cultures of Basidiomycetes, allowing the production of innovative protein-polysaccharide compounds (Arteiro, et al. 2012, Salvador, et al. 2012). These complexes show no toxicity in Artemia salina after 24 hours of incubation and caused no hepatotoxicity in in vivo assays using W...
Glutathione reductase play a key role in the differential response of Saccharom...
Candeias, M; Alves-Pereira, I; Ferreira, RuiThe isoproturon is a systemic herbicide applied in pre- and post-emergence control of annual grasses and broad-leaved weeds in winter crops that block photosynthesis, being listed by European Union as special substance that threaten the earth surface. Probably, can generate reactive oxygen species blocking the respiratory chain and cause oxidative stress and cell death. So, the main purpose of this study was to...
Protein–polysaccharides of Trametes versicolor: production
Arteiro, J M; Martins, M R; Salvador, C; Candeias, M F; Karmali, A; Caldeira, A TeresaAbstract Extracellular- (E-PPS) and intracellular-protein– polysaccharides (I-PPS) complexes were produced by Trametes versicolor in submerged cultures with different carbon sources. The highest extracellular-(EPS) and intracellular- polysaccharide (IPS) concentration in the complexes was obtained with tomato pomace culture. DPPH radical scavenging for E-PPS and I-PPS produced by liter of culture was equivallen...
Isoproturon increases Saccharomyces cerevisiae UE-ME3 proliferation, blocking N...
Candeias, M; Alves-Pereira, I; Ferreira, RuiThe isoproturon (IPU) is an herbicide used in Autumn-Winter crops that often persists in soils and aquifers at levels considered toxic by European legislation. In eukaryotic cells the IPU can generate ROS and consequently oxidative stress and it may be involved in triggering of serious illnesses like cancer. Accordingly, it is urgent to find microorganisms useful in bioremediation of this phenylurea. The aim of...
Isoproturon induce Saccharomyces cerevisiae UE-ME3 proliferation in glucose sta...
Candeias, M; Alves-Pereira, I; Ferreira, RuiIsoproturon (IPU), an herbicide used in winter crops, often persists in soils and aquifers at levels considered toxic by European legislation. Whereas it may be involved in triggering of serious illnesses, it’s urgent to find microorganisms that could contribute to its elimination. The main purpose of this study was to evaluate the effect of IPU on the antioxidant response of the wine-wild Saccharomyces cerevis...
Toxicity of isoproturon on Saccharomyces cerevisiae growing in mineral medium d...
Candeias, M; Alves-Pereira, I; Ferreira, RuiThe results revealed an increase of viable cells, after 72 h of culture and an increase of antioxidant power mediated by GSH and GR activity in S. cerevisiae UE-ME3. The adaptive response of UE-ME3 strain to isoproturon, determined in MB, was clearly higher than observed in IGC-3507 strain. So, we presume that the extent of the toxic effect of isoproturon in both yeast strains depends on glutathione-mediated an...
Fenilureias diminuem a actividade enzimática glucose-6-P desidrogenase de Sacch...
Tenda, H; Candeias, M; Pinheiro, M; Alves-Pereira, I; Ferreira, ROs resultados mostram que as duas fenilureias diminuem significativamente esta actividade catalítica em células em fase replicativa e senescente, expostas a níveis superiores a 25 µM, sendo esse efeito superior na presença de diurão, facto que evidencia uma maior toxicidade deste composto, por bloqueio energético e da divisão celular. Contudo observou-se um incremento significativo desta actividade enzimática e...
| Financiadores do RCAAP | |||||||
|
|
|
|
|
|
||