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Total Laparoscopic Hysterectomy: Retrospective Analysis of 262 Cases
Introduction: Hysterectomy is one of the most common gynecological procedures and may be performed either by vaginal approach, laparotomy or laparoscopy. Although total laparoscopic hysterectomy has multiple advantages, conflicting major complication rates have been previously reported.Objectives: To describe our experience performing TLH and to evaluate complication rates.Material and Methods: A retrospective ...
Angiogenesis as a Therapeutic Target in Endometriosis
Introduction: Angiogenesis is a key factor for the successful establishment and growth of endometriotic lesions.Material and Methods: We performed a literature search in PubMed and reviewed the most pertinent studies published until January 2014 and focused on the endometriosis-associated angiogenesis and/or anti-angiogenic strategies for the treatment of this gynecological disorder.Results: The present review ...
Incorrect DNA methylation of the DAZL promoter CpG island associates with defec...
Navarro-Costa, Paulo; Nogueira, Paulo; Carvalho, Marta; Leal, Fernanda; Cordeiro, Inês; Calhaz-Jorge, Carlos; Gonçalves, João; Plancha, Carlos E.Versão impressa: Hum Reprod. 2010 Oct;25(10):2647-54 ; Background: Successful gametogenesis requires the establishment of an appropriate epigenetic state in developing germ cells. Nevertheless, an association between abnormal spermatogenesis and epigenetic disturbances in germline-specific genes remains to be demonstrated. Methods: In this study, the DNA methylation pattern of the promoter CpG island (CGI) of ...
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