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Growth cartilage expression of growth hormone/insulin-like growth factor I axis...

INTRODUCTION: Catch-up growth following the cessation of a growth inhibiting cause occurs in humans and animals. Although its underlying regulatory mechanisms are not well understood, current hypothesis confer an increasing importance to local factors intrinsic to the long bones' growth plate (GP). AIM: The present study was designed to analyze the growth-hormone (GH)-insulin-like growth factor I (IGF-I) axis i...