Encontrados 6 documentos, a visualizar página 1 de 1
Evolution of the Human Immunodeficiency Virus Type 2 Envelope in the First Year...
Rocha, C; Calado, R; Borrego, P; Marcelino, JM; Bártolo, I; Rosado, L; Cavaco-Silva, P; Gomes, P; Família, C; Quintas, A; Skar, H; Leitner, TBackground: Differently from HIV-1, HIV-2 disease progression usually takes decades without antiretroviral therapy and the majority of HIV-2 infected individuals survive as elite controllers with normal CD4+ T cell counts and low or undetectable plasma viral load. Neutralizing antibodies (Nabs) are thought to play a central role in HIV-2 evolution and pathogenesis. However, the dynamic of the Nab response and r...
Papilomatose Respiratória Recorrente
Viegas, V; Calado, R; Marques, A; Cunha Sá, I; Barata, DA papilomatose respiratória recorrente da criança é uma doença rara, mas potencialmente ameaçadora da vida, e que atinge o trato respiratório com predilecção pela laringe e traqueia. É causada pelo papiloma-vírus humano (tipo 6 e 11). É uma das causas de rouquidão e obstrução da via aérea. É necessário um elevado grau de suspeição diagnóstica, tendo em conta as várias formas de apresentação. Apresenta-se o caso...
Age-related changes of the multidrug resistance P-glycoprotein function in norm...
Machado,C.G.; Calado,R.T.; Garcia,A.B.; Falcão,R.P.The multidrug resistance P-glycoprotein is a transmembrane efflux pump expressed by lymphocytes and is involved in their cytolytic activity. In the present study, we investigated the age-related changes of P-glycoprotein function in normal peripheral blood lymphocytes. Blood samples from 90 normal volunteers (age range, 0 to 86 years) were analyzed. P-glycoprotein function was assessed by the flow cytometric rh...
HFE gene mutations in coronary atherothrombotic disease
Calado,R.T.; Franco,R.F.; Pazin-Filho,A.; Simões,M.V.; Marin-Neto,J.A.; Zago,M.A.Although iron can catalyze the production of free radicals involved in LDL lipid peroxidation, the contribution of iron overload to atherosclerosis remains controversial. The description of two mutations in the HFE gene (Cys282Tyr and His63Asp) related to hereditary hemochromatosis provides an opportunity to address the question of the association between iron overload and atherosclerosis. We investigated the p...
The oral health care programme of Cartaxo. Assessment of its impact.
Calado, R M; Public Health Department, Oral Health Division, General Directorate for Primary Health Care, Lisbon.The Cartaxo Municipality has been developing a primary oral health care program since 1988. It is based on national programs of oral health promotion and prevention of dental caries (Oral Health Technical Guidelines on Mother & Child Health and Oral Program in Schools) of the Primary Health Care Administration, and includes the application of pit and fissure sealants on the occlusal surface of the first permane...
The oral health care program of Cartaxo. An evaluation of its impact.
Calado, R M; Departamento de Saúde Pública, Lisboa.The Cartaxo Municipality has been developing a Primary Oral Health Care program since 1988. It is based on national programs of oral health promotion and prevention of dental caries (Oral Health Technical Guidelines on Mother & Child Health and Oral Program in Schools) of the Primary Health Care Administration, and includes the application of pit and fissure sealants on the occlusal surface of the first permane...
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