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Effect of dithiocarbamate thiram on Wistar rat growth plate and articular carti...
Fialho, L; Rafael, A; Cabrita, AS; Pereira, AMF; Capela e Silva, FAvaliou-se o efeito do tirame, ditiocarbamato largamente utilizado na agricultura como antifúngico e repelente de roedores, na ossificação endocondral de mamíferos, usando, como modelo, ratos Wistar. Não foram observadas lesões na cartilagem articular, nem nas placas de crescimento, o que pode ser atribuído à dose utilizada e à duração do ensaio. A diminuição da altura da placa de crescimento nos animais aos qu...
Effects of the food contaminant semicarbazide on testicular morphology of juven...
Ramos, A; Pereira, AMF; Cabrita, AS; Capela e Silva, FO objectivo do presente trabalho foi avaliar os efeitos da semicarbazida na morfologia testicular de ratos Wistar jovens. Os animais foram tratados durante 30 dias com hidrocloreto de semicarbazida incorporado na dieta, nas concentrações de 0, 3 e 6g/kg. Os resultados obtidos revelaram uma diminuição estatisticamente significativa no diâmetro dos túbulos seminíferos, no diâmetro do lúmen dos túbulos seminíferos...
Efeitos da semicarbazida no esqueleto de ratos Wistar em crescimento.
Ramos, A; Pereira, AMF; Cabrita, AS; Capela e Silva, FThe effects of semicarbazide hydrochloride on skeletal tissues were evaluated using Wistar rats. In the animals submitted to the administration of semicarbazide, radiological examination showed bone and articular alterations with growth plates enlargement. Histological exams showed irregular patterns and proliferation of chondrocytes and excessive accumulation of extracellular matrix. Immunohistochemical exams ...
Effects of hexavalent chromium on bone growth in juveniles Wistar rats
Rafael, A; Alpoim, C; Cabrita, AS; Capela e Silva, FWorkers at industrial settings, as well as the population in general is at risk of health problems caused by contaminating wastes, inadequate treated for their safe disposal. As result, certain toxic substances, such as hexavalent chromium [Cr(VI)] compounds, contaminate tap water and have reached the general population including children. The present study was undertaken to evaluate the effects of Cr(VI), in t...
Processing and classification of biological images: Application to histology
Nunes, B; Rato, Luis; Capela e Silva, F; Rafael, A; Cabrita, ASThis article deals with a histological problem by using image processing and feature extraction in images of renal tissues of rats and their classification through various methods such as: Bayesian inference, decision trees and support vector machines.
Expressão da caderina na discondroplasia tibial
Capela e Silva, F; Lamy, E; Pereira, A; Potes, J; Cabrita, ASBy immunohistochemistry the expression of a pan-cadherin antibody that recognizes a wide variety of cadherins in chondrocytes from normal and tibial dyschondroplasia (TD) growth plates was compared. Surprisingly, an upregulated expression that was not expected in TD lesion chondrocytes was observed. The reason for this apparent upregulation is not clear. The increased expression may simply be due to the particu...
Expressão imunoistoquímica da proteína S-100 na discondroplasia da tíbia
Capela e Silva, F; Lamy E, E; Reis, J; Potes, J; Pereira, A; Cabrita AS, ASIt was compared, by immunohistochemistry, the expression of S-100 protein from normal and tibial dyschondroplasia (TD) growth plates. The results suggest that S-100 may be involved in growth plate homeostasis. The expression of S-100 in dyschondroplastic chondrocytes may be due to a low level of calcium in the lesion and/or compression of chondrocytes by the accumulated matrix. One further possibility is the as...
Incorporation of impacted morselized bone allografts in rabbits
Judas, F; Figueiredo, MH; Cabrita, AS; Proença, AMorselized bone allografts have been used for the treatment of bone stock loss in orthopedic revision surgery with encouraging results. However, several parameters can influence the graft incorporation including the processing treatments. This experimental work used a cavitary bone defect in 90 rabbits to evaluate the sequence of incorporation of three different kinds of morselized bone allografts: uncryopreser...
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