Encontrados 14 documentos, a visualizar página 1 de 2
Alterações histológicas dos rins e expressão das metalotioneínas e das proteína...
Paiva, F.; Fialho, L.; Cabrita, A.S.; Pereira, A.M.F; Capela e Silva, F.The histological alterations and the expression of metallothionein (MTs) and heat shock protein (Hsp70) in the kidney of Wistar rats after thiram fungicide exposure were evaluated. Animals were distributed into three groups: standard diet group, standard diet + corn oil group and thiram group. Significant differences were found (P<0,05) in the evolution of body weight between rats in the thiram group and those ...
Haematological and biochemical parameters in Churra-da-Terra-Quente ewes from t...
Dias,I.R.; Viegas,C.A.; Silva,A.M.; Pereira,H.F.; Sousa,C.P.; Carvalho,P.P.; Cabrita,A.S.; Fontes,P.J.; Silva,S.R.; Azevedo,J.M.T.Hematological and biochemical parameters, including plasma electrolytes and thyroid hormones, were determined in 73 clinically healthy Churra-da-Terra-Quente ewes, a typical breed from the northeast of Portugal. The hemogram values were: erythrocytes 9.8±1.5×10(12)/L; haemoglobin 118.1±19.1g/L; haematocrit 40.8±5.9%; leukocytes 5.7±1.8×10(9)/L; and platelets 544.3±177.2×10(9)/L. The thrombin time was 17.3±1.7 s...
Expressão da caderina na discondroplasia tibial
Capela e Silva,F.; Lamy,E.; Pereira,A.; Reis,J.C.; Potes,J.C.; Cabrita,A.S.
Expressão imunoistoquímica da proteína S-100 na discondroplasia da tíbia
Capela e Silva,F.; Lamy,E.; Reis,J.C.; Potes,J.C.; Pereira,A.; Cabrita,A.S.
Haematological and biochemical parameters in Churra-da-Terra-Quente ewes from t...
Dias, Isabel R.; Viegas, Carlos A.; Silva, A. M.; Pereira, H. F.; Sousa, C. P.; Carvalho, P. P.; Cabrita, A. S.; Fontes, P. J.; Silva, S. R.Hematological and biochemical parameters, including plasma electrolytes and thyroid hormones, were determined in 73 clinically healthy Churra-da-Terra-Quente ewes, a typical breed from the northeast of Portugal. The hemogram values were: erythrocytes 9.8±1.51012/L; haemoglobin 118.1±19.1g/L; haematocrit 40.8±5.9%; leukocytes 5.7±1.8109/L; and platelets 544.3±177.2109/L. The thrombin time was 17.3±1.7 seconds...
Haematology, genotoxicity, enzymatic activity and histopathology as biomarkers ...
Sánchez-Chardi, A.; Marques, C. C.; Gabriel, S. I.; Capela-Silva, F.; Cabrita, A. S.; López-Fuster, M. J.; Nadal, J.; Mathias, M. L.Haematological (WBC, RBC, Hgb and Hct) and genotoxicity (MNT) parameters, hepatic enzymatic activities (GST, GPx and GR), and a histopathological evaluation of liver, kidneys and gonads were assessed as general biomarkers of metal pollution in the shrew Crocidura russula inhabiting a pyrite mining area. Specimens exposed to metals presented a few significant alterations when compared with reference animals: GST...
The Sheep as an Animal Model in Orthopaedic Research
Potes, J.C.; Reis, J.; Capela e Silva, Fernando; Relvas, C.; Cabrita, A.S.; Simões, J.A.The use of sheep as model in remodeling process in cancelous and cortical bone for the assessment of new orthopaedic biomaterials and implants, in biomechanical studies and as model for tissue-engineered bone constructs has been described in the literature. Sheep are a well accepted model for in vivo studies in orthopaedic research to address the biomechanical, biochemical and histological processes of bone bio...
Assessment of bone formation markers under controlled environmental conditions ...
Dias, Isabel R.; Viegas, Carlos A.; Azevedo, Jorge T.; Costa, E. M.; Lourenço, P.; Rodrigues, A.; Cabrita, A. S.Eighteen healthy skeletally mature (3 years old) ewes, with an average weight of 45 kg, of the Portuguese Churra da Terra Quente breed were used to evaluate the normal values of total and bone-specific isoform of alkaline phosphatase serum activities (ALP and BALP, respectively) and serum osteocalcin (OC) and their correlation with the serum minerals – calcium (Ca), phosphorus (P), magnesium (Mg) and ionized ca...
Evaluation of the antitumoral effect mediated by IL-12 and HSV-tk genes when de...
Faneca, H.; Cabrita, A. S.; Simões, S.; Lima, M. C. Pedroso deIn the present work, we used a novel albumin-associated lipoplex formulation, containing the cationic lipid 1-palmitoyl-2-oleoyl-sn-glycero-3-ethylphosphocholine (EPOPC) and cholesterol (Chol), to evaluate the antitumoral efficacy of two gene therapy strategies: immuno-gene therapy, mediated by IL-12 gene expression, and "suicide" gene therapy, mediated by HSV-tk gene expression followed by ganciclovir (GCV) tr...
Discondroplasia da tíbia como modelo em estudos de mecanobiologia experimental
Capela e Silva, Fernando; Costa Reis, J.; Potes, J.C.; Cabrita, A.S.A discondroplasia da tíbia, consiste numa anomalia espontânea, ou induzida, nas placas de crescimento epifisárias dos ossos longos, das estirpes de rápido crescimento das espécies avícolas, caracterizada pelo aparecimento de uma massa cartilagínea avascular opaca, não calcificada, que se estende até à metáfise, numa zona em que, normalmente, existe osso trabecular. Do ponto de vista citológico, a discondroplasi...
| Financiadores do RCAAP | |||||||
|
|
|
|
|
|
||