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Monozygotic twin sisters discordant for familial hemiplegic migraine

Barros, J.; Barreto, R.; Brandão, A.; Domingos, J.; Damásio, J.; Ramos, C.; Lemos, C.; Sequeiros, J.; Alonso, I.; Pereira-Monteiro, J.

Background: The high concordance rate of migraine in monozygotic twin pairs has long been recognised. In the current study, we present a monozygotic twin pair discordant for familial hemiplegic migraine (FHM). Case presentations: We evaluated 12 adult family members in 2012. The twin pair was separately examined by neurologists at different time points. Mutation screening was performed for known FHM-related gen...


Transponder for Coarse Wavelength Division Multiplexing (CWDM) Optical Communic...

V. Barbosa; A. N. Pinto; C. Lemos; R. M. Diz; N. J. Carvalho

In this paper a CWDM bi-directional opticaltransponder is described. This transponder was built in theframework of the project SIRAC. The design optionsfollowed are detailed discussed. This paper also discusses thepossible extension of the transponder to Dense WavelengthDivision Multiplexing (DWDM) systems.Znda Terms - Optical Transponder, CWDM Systems,DWDM Systems, FEC. ; Neste artigo é feita a descri&...

Data: 2011   |   Origem: Electrónica e Telecomunicações

Persister cells in a biofilm treated with a biocide

Simões, Lúcia C.; Lemos, Madalena; Pereira, Ana M.; Abreu, Ana C.; Saavedra, Maria J.; Simões, M.

This study investigated the physiology and behaviour following treatment with ortho-phthalaldehyde (OPA), of Pseudomonas fluorescens in both the planktonic and sessile states. Steady-state biofilms and planktonic cells were collected from a bioreactor and their extracellular polymeric substances (EPS) were extracted using a method that did not destroy the cells. Cell structure and physiology after EPS extractio...


The effects of glutaraldehyde on the control of single and dual biofilms of Bac...

Simões, Lúcia C.; Lemos, Madalena; Araújo, Paula; Pereira, Ana M.; Simões, M.

Glutaraldehyde (GLUT) was evaluated for control of single and dual species biofilms of Bacillus cereus and Pseudomonas fluorescens on stainless steel surfaces using a chemostat system. The biofilms were characterized in terms of mass, cell density, total and matrix proteins and polysaccharides. The control action of GLUT was assessed in terms of inactivation and removal of biofilm. Post-biocide action was chara...


Antifungal activity of the naphthoquinone beta-lapachone against disseminated i...

Medeiros,C.S.; Pontes-Filho,N.T.; Camara,C.A.; Lima-Filho,J.V.; Oliveira,P.C.; Lemos,S.A.; Leal,A.F.G.; Brandão,J.O.C.; Neves,R.P.

The in vivo antifungal activity of the naphthoquinone beta-lapachone against disseminated infection by Cryptococcus neoformans was investigated. Swiss mice were immunosuppressed daily with dexamethasone (0.5 mg per mouse) intraperitoneally for 3 days, the procedure was repeated 4 days later, and the animals were then challenged intravenously with C. neoformans (10(6) CFU/mL) 1 week later. Seven days after infec...

Data: 2010   |   Origem: OASIS br

Bioacetilação de álcoois catalisada por Saccharum officinarum

Assunção,João Carlos C.; Lemos,Telma Leda G.; Monte,Francisco José Q.

Lipase-catalysed esterifications of alcohols using immobilized enzyme system from sugar cane (Saccharum officinarum) as biocatalyst afforded the corresponding esters in considerable yields (68-93%). Under optimized conditions, the material was utilized for reactions of acetylation with several advantage. It also investigated the possibility of reuse of immobilized enzymes of S. officinarum as biocatalyst under ...

Data: 2009   |   Origem: OASIS br

Effect of preparation conditions on morphology, drug content and release profil...

Bazzo,G. C.; Lemos-Senna,E.; Gonçalves,M. C.; Pires,A. T. N.

In this study, poly(hydroxybutyrate) microparticles containing piroxicam were prepared by the oil-in-water emulsion-solvent evaporation method. The effects of some process conditions on drug content were determined using a 2³ factorial design. The piroxicam loading efficiency varied from 5.5 to 89.8 %. Hollow and irregular microparticles with drug crystals on their surfaces were obtained when 5 mL of chloroform...

Data: 2008   |   Origem: OASIS br

A new eremophilane-type sesquiterpene from the phytopatogen fungus Lasiodiplodi...

Nunes,Fátima M.; Oliveira,Maria da Conceição F. de; Arriaga,Ângela M. C.; Lemos,Telma L. G.; Andrade-Neto,Manoel; Mattos,Marcos C. de; Mafezoli,Jair

The phytopatogenic fungus Lasiodiplodia theobromae, isolated from guava, was cultivated in rice for 32 days at room temperature. Extraction with CH2Cl2:MeOH (3:7), followed by chromatography fractionation of the extract provided ergosterol. From the fungus culture in Czapeck medium for 40 days at room temperature, were isolated isocoumarin cis-4-hydroxymeleine and an eremophilane-type sesquiterpene. The latter ...

Data: 2008   |   Origem: OASIS br

Geração de tecnologias para o manejo sustentável de flores tropicais e temperad...

VIÉGAS, I. de J. M.; FRAZÃO, D. A. C.; CHU, E. Y.; CONCEIÇÃO, H. E. O. da; SOUZA, L. A. de; POLTRONIERI, M. C.; LEMOS, O. F. de; OLIVEIRA, R. F. de

2008 ; Disponível também on-line.

Data: 2008   |   Origem: OASIS br

Aplicação de Al-PILC na adsorção de Cu2+, Ni2+e Co2+ utilizando modelos físico-...

Guerra,D. L.; Airoldi,C.; Lemos,V. P.; Angélica,R. S.; Viana,R. R.

Amostra de esmectita pertencente a Serra de Maicuru (Estado do Pará, Norte do Brasil, região amazônica) foi pilarizada com Al13, A Argila pilarizada com alumínio (Al-PILC) foi caracterizada por DRX, MEV e EDS. Para a análise textural foram utilizadas isotermas de adsorção-desorção utilizando o nitrogênio. Este artigo é dirigido ao estudo da adsorção de metais pesados. A adsorção dos íons de Cu2+, Ni2+e Co2+ foi...

Data: 2007   |   Origem: OASIS br

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    Financiadores do RCAAP

Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia