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Transplantation in Highly Sensitised Patients Treated with Intravenous Immunogl...

Ferreira, AC; Brum, S; Fernandes, V; Buinho, F; Viana, H; Alcântara, P; Ferreira, A; Candeias, N; Sousa, J; Lima, A; Carvalho, F; Trindade, H

Renal transplant in highly sensitised patients is associated with increased morbidity. The aim of this retrospective study was to evaluate the clinical evolution of 30 highly sensitised deceased donor kidney transplants and the influence of different timing of B cell directed treatment and its importance in the outcome of these patients. All recipients had negative complement dependent lymphocytotoxicity cytoto...


Leukopenia in Kidney Transplant Patients with the Association of Valganciclovir...

Brum, S; Nolasco, F; Sousa, J; Ferreira, A; Possante, M; Pinto, JR; Barroso, E; Ribeiro Santos, J

Cytomegalovirus (CMV) is the most common viral infection after transplantation. Valganciclovir (VGC) is established for prophylaxis and treatment of CMV infections, but leukopenia which appears in 10% to 13% (severe in 4.9%) is the principal side effect. We have recently noted an increased incidence of leukopenia and severe neutropenia among our renal transplant patients and thought to identify the associated f...


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Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia