This article is concerned with the third sector (in particular, local development agencies, arts and culture organisations) in relation to opportunities, barriers, and challenges they face and their potential roles within the context of tourism planning and development. These organisations often perform a central role as keepers and nurturers of a region’s identity and traditions, often supplementing the state ...
Este artigo apresenta os resultados de uma pesquisa que teve como objetivo principal caracterizar o contexto e as práticas relacionadas ao uso de agrotóxicos entre agricultores residentes na Serrinha do Mendanha, comunidade agrícola situada em Campo Grande, município do Rio de Janeiro. A proposta metodológica teve uma abordagem qualitativa, sendo a principal fonte de dados a aplicação de questionário semiestrut...
http://www.sciencedirect.com/science/article/B6T12-4V0MTG8-1/2/7b7f3913eea3a6f05047e8c1927696a9
The Brazilian city of Três Lagoas, Mato Grosso do Sul State, has experienced an urban outbreak of visceral leishmaniasis since 2000. In 2002, due to the increase in the number of cases, 46 families with cases of visceral leishmaniasis were studied to verify the prevalence of asymptomatic infection in household contacts. Indirect immunofluorescence and ELISA showed a 36.4% positive infection rate. There were no ...
Abstract Resveratrol (3,4',5-trihydroxystilbene) is a phytochemical believed to be partly responsible for the cardioprotective effects of red wine due to its numerous biological activities. Here, we studied biochemical pathways underlying peroxynitrite-mediated apoptosis in endothelial cells and potential mechanisms responsible for resveratrol cytoprotective action. Peroxynitrite triggered endothelial cell apo...
A aterosclerose, principal causa de morte nos países com estilo de vida ocidental, é uma doença inflamatória crónica associada a stress oxidativo. Inicialmente, pensou-se que o papel do stress oxidativo na aterosclerose, em consequência de um aumento da concentração de espécies reactivas de oxigénio e de nitrogénio na parede arterial, tais como o peroxinitrito (ONOO-), se restringia à oxidação das lipoproteínas...
Atherosclerosis, the main cause of cardiovascular disease (CD), is a chronic inflammatory condition associated with an overproduction of oxidant species, namely peroxynitrite, which is a powerful oxidant that reacts directly with all biomolecules. Glutathione is an efficient scavenger of peroxynitrite, so, modulation of glutathione synthesis may provide a strategy to selectively protect cells from this oxidant....
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