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Characterization of modular bacteriophage endolysins from giant phiKZ related m...

Peptidoglycan lytic enzymes (endolysins) of bacteriophages have a major role in bacterial lysis at the end of the phage replication cycle. These endolysins turned out to be potential antibacterial compounds to combat a broad range of Gram-positive pathogens, yet Gram-negative bacteria remain unharmed due to their impermeable outer membrane. With this background, we recently characterized three new endolysins fr...