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Diversity and phylogeny of the Helicobacter pylori outer membrane protein-encod...

Cordeiro, Rita; Ménard, Armelle; Breurec, Stéphane; Mégraud, Francis; Oleastro, Mónica

The genetic diversity and evolution of the homC gene was evaluated in a panel of approximately 200 clinical and reference strains, isolated from patients from different geographical origins and presenting different gastric diseases. PCR, sequencing and bioinformatics analyses were used. All the strains tested harboured a complete homC gene at a conserved locus. Phylogenetic reconstruction of homC showed a geogr...


High worldwide conservation of a Helicobacter pylori outer membrane protein

Ménard, Armelle; Cordeiro, Rita; Breurec, Stéphane; Mégraud, Francis; Oleastro, Mónica

The genetic diversity and evolution of homD, coding for Helicobacter pylori outer membrane protein (OMP) was investigated in a panel of approximately 200 clinical and reference strains, isolated from patients from different geographical origins and presenting different gastric diseases. PCR, sequencing and bioinformatics analyses were used. The homD gene was present in all strains, at a conserved locus, and sho...


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    Financiadores do RCAAP

Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia