Encontrados 32 documentos, a visualizar página 1 de 4
Poly(glutamic acid) nanofibre modified glassy carbon electrode: Characterizatio...
Santos, Daniela Pereira; Zanoni, Maria Valnice Boldrin; Bergamini, Márcio Fernando; Chiorcea-Paquim, Ana-Maria; Diculescu, Victor ConstantinGlassy carbon electrodes (GCE) were modified with poly(glutamic acid) acid films prepared using three different procedures: glutamic acid monomer electropolymerization (MONO), evaporation of poly(glutamic acid) (PAG) and evaporation of a mixture of poly(glutamic acid)/glutaraldehyde (PAG/GLU). All three films showed good adherence to the electrode surface. The performance of the modified GCE was investigated by...
Bioelectrochemistry
Brett, Ana Maria Oliveirahttp://www.sciencedirect.com/science/article/B6W72-4JNF072-B/1/805755cd8047acbe3cebaafcfff34ebc
Redox Behavior of Anthocyanins Present in Vitis vinifera L.
Janeiro, Patricia; Brett, Ana Maria OliveiraVoltammetric techniques were employed to study the electrochemical behavior of several anthocyanins. The redox behavior of anthocyanins with the same basic structure, the influence of glycosylation on the redox behavior of anthocyanins derived from different anthocyanidins, and the influence of methoxylation were investigated. The anthocyanins used in this study were malvidin-3-O-glucoside chloride, malvidin-3,...
Electrochemistry of Nucleic Acids and Proteins. Towards Electrochemical Sensors...
Brett, Ana Maria Oliveirahttp://www.sciencedirect.com/science/article/B6TG0-4K4WH6N-2/1/d5250cbf6497d379855f15accfac068b
Atomic force microscopy characterization of synthetic pyrimidinic oligodeoxynuc...
Paquim, Ana-Maria Chiorcea; Oretskaya, Tatiana S.; Brett, Ana Maria OliveiraIn order to better understand the adsorption mechanism of nucleic acids at electrode surface, MAC Mode atomic force microscopy (MAC Mode AFM) was used to investigate the adsorption of a 10-base synthetic oligodeoxynucleotide (ODN) with the sequence 5'-CTTTTTCTTT-3' containing only pyrimidinic bases, onto a highly oriented pyrolytic graphite (HOPG) electrode. Free adsorption and adsorption at applied potentials ...
Adsorption of synthetic homo- and hetero-oligodeoxynucleotides onto highly orie...
Paquim, Ana-Maria Chiorcea; Oretskaya, Tatiana S.; Brett, Ana Maria OliveiraDNA adsorption on electrode surfaces is of fundamental interest for the development of DNA-based biosensors. The free adsorption of 10-mer synthetic oligodeoxynucleotides (ODNs) onto highly oriented pyrolytic graphite (HOPG) surfaces was studied using Magnetic AC mode atomic force microscopy (MAC Mode AFM). The mechanism of interaction of nucleic acids with carbon electrode surfaces was elucidated, using 10-mer...
Editorial
Brett, Ana Maria Oliveirahttp://www.sciencedirect.com/science/article/B6TG0-4JW7X04-9/1/e839ed9a3d5631f25adada92860abac2
On the Electrochemical Oxidation of Resveratrol
Corduneanu, Oana; Janeiro, Patricia; Brett, Ana Maria OliveiraResveratrol (3,5,4prime-trihydroxystilbene) is an organic metabolite produced by plants in response to fungal infection. It is found in various plant fruits and is abundant in the skins of unripe grapes and related products. This photosensitive molecule exists in two isomeric forms, trans and cis-resveratrol. The antioxidant activity of resveratrol, both trans and cis forms, was evaluated by means of cyclic, di...
Voltammetric Behavior of Antileukemia Drug Glivec. Part III: In Situ DNA Oxidat...
Diculescu, Victor Constantin; Vivan, Marilene; Brett, Ana Maria OliveiraGlivec is a relatively small molecule with activity against the protein tyrosine kinase, a protein expressed by all patients with chronic myelogenous leukemia (CML). Based on its activity on CML, glivec is undergoing extensive evaluation of its activity against other types of tumor. As a result, there is an ongoing need for clarification of glivec pharmacokinetics so that issues such as drug-biomolecular comple...
Voltammetric Behavior of Antileukemia Drug Glivec. Part II - Redox Processes of...
Diculescu, Victor Constantin; Vivan, Marilene; Brett, Ana Maria OliveiraGlivec is a newly developed drug that belongs to the class of 2-phenylaminopyrimidine. It is a potent inhibitor of ABL-kinase, the main clinical manifestation of chronic myelogenous leukemia (CML). Based on its activity on CML, glivec is undergoing extensive evaluation for its activity against other tumor types. Detection and quantitation of glivec in biological fluids or cells is thus very important. The antil...
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