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Factors related with adiponectinemia in obese and normal-weight women and with ...
Silva-Nunes, José; Oliveira, Ana; Duarte, Leone; Barradas, Margarida; Melão, Alice; Brito, Miguel; Veiga, LuísaObjective: To assess different factors influencing adiponectinemia in obese and normal-weight women; to identify factors associated with the variation (Δ) in adiponectinemia in obese women following a 6-month weight loss program, according to surgical/non-surgical interventions. Methods: We studied 100 normal-weight women and 112 obese premenopausal women; none of them was on any medical treatment. Women were c...
Q192R polymorphism of the paraoxonase-1 gene as a risk factor for obesity in Po...
Veiga, Luísa; Silva-Nunes, José; Melão, Alice; Oliveira, Ana; Duarte, Leone; Brito, MiguelIntroduction - Obesity became a major public health problem as a result of its increasing prevalence worldwide. Paraoxonase-1 (PON1) is an esterase able to protect membranes and lipoproteins from oxidative modifications. At the PON1 gene, several polymorphisms in the promoter and coding regions have been identified. The aims of this study were i) to assess PON1 L55M and Q192R polymorphisms as a risk factor for ...
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