Encontrados 2 documentos, a visualizar página 1 de 1
Cross-Functioning between the Extraneuronal Monoamine Transporter and Multidrug...
Costa, Vera Marisa; Ferreira, Luísa Maria; Branco, Paula Sério; Carvalho, Félix; Bastos, Maria Lourdes; Carvalho, Rui Albuquerque; Carvalho, MárciaIsolated heart cells are highly susceptible to the toxicity of catecholamine oxidation products, namely, to catecholamine-glutathione adducts. Although cellular uptake and/or efflux of these products may constitute a crucial step, the knowledge about the involvement of transporters is still very scarce. This work aimed to contribute to the characterization of membrane transport mechanisms, namely, extraneuronal...
Oxidation Process of Adrenaline in Freshly Isolated Rat Cardiomyocytes: Formati...
Costa, Vera Marisa; Silva, Renata; Ferreira, Luísa Maria; Branco, Paula Sério; Carvalho, Félix; Bastos, Maria Lourdes; Carvalho, Rui AlbuquerqueHigh concentrations of circulating biogenic catecholamines often exist during the course of several cardiovascular disorders. Additionally, coronary dysfunctions are prominent and frequently related to the ischemic and reperfusion phenomenon (I/R) in the heart, which leads to the release of large amounts of catecholamines, namely adrenaline, and to a sustained generation of reactive oxygen species (ROS). Thus, ...
| Financiadores do RCAAP | |||||||
|
|
|
|
|
|
||