Encontrados 8 documentos, a visualizar página 1 de 1

Causa Inesperada de Disfunção Sistólica em Octogenária

Antinociception synergy between the peripheral and spinal sites of the heme oxy...

We have shown that the peripheral and spinal cord heme oxygenase (HO)-carbon monoxide (CO)-soluble guanylate cyclase-cGMP pathways play an important role in antinociception in the rat experimental formalin model. Our objective was to determine if there is synergism between peripheral (paw) and spinal HO-CO pathways in nociception. Rats were handled and adapted to the experimental environment for a few days befo...

Glutamatergic neurotransmission modulates hypoxia-induced hyperventilation but ...

The interaction between pulmonary ventilation (V E) and body temperature (Tb) is essential for O2 delivery to match metabolic rate under varying states of metabolic demand. Hypoxia causes hyperventilation and anapyrexia (a regulated drop in Tb), but the neurotransmitters responsible for this interaction are not well known. Since L-glutamate is released centrally in response to peripheral chemoreceptor stimulati...

The importance of glucose for the freezing tolerance/intolerance of the anuran ...

Several species of terrestrially hibernating frogs, turtles and insects have developed mechanisms, such as increased plasma glucose, anti-freeze proteins and antioxidant enzymes that resist to freezing, for survival at subzero temperatures. In the present study, we assessed the importance of glucose to cryoresistance of two anuran amphibians: the frog Rana catesbeiana and the toad Bufo paracnemis. Both animals ...

Participation of nitric oxide in the nucleus isthmi in CO2-drive to breathing i...

The nucleus isthmi (NI) is a mesencephalic structure of the amphibian brain. It has been reported that NI plays an important role in integration of CO2 chemoreceptor information and glutamate is probably involved in this function. However, very little is known about the mechanisms involved. Recently, it has been shown that nitric oxide synthase (NOS) is expressed in the brain of the frog. Thus the gas nitric ox...

Role of nitric oxide in hypoxia-induced hyperventilation and hypothermia: parti...

Hypoxia elicits hyperventilation and hypothermia, but the mechanisms involved are not well understood. The nitric oxide (NO) pathway is involved in hypoxia-induced hypothermia and hyperventilation, and works as a neuromodulator in the central nervous system, including the locus coeruleus (LC), which is a noradrenergic nucleus in the pons. The LC plays a role in a number of stress-induced responses, but its part...

Imaturidade imunológica fetal e neonatal: implicações na evolução clínica da in...

Crianças infectadas pelo HIV-1, por via vertical, apresentam uma evolução clínica mais grave do que crianças infectadas por outras vias e adultos. A imaturidade fisiológica dos sistemas imunitários fetal e neonatal, no momento da infecção, parece ter papel crucial na progressão da infecção pelo HIV-1 em crianças. Neste artigo, fazemos revisão da ontogenia do sistema imunológico humano, correlacionando-a com a i...

HIV antibodies in beggar blood donors in Rio de Janeiro, Brazil - II