Encontrados 3 documentos, a visualizar página 1 de 1
Mitochondrial disruption occurs downstream from β-adrenergic overactivation by ...
Branco, Ana F.; Sampaio, Susana F.; Wieckowski, Mariusz R.; Sardão, Vilma A.; Oliveira, Paulo J.β-Adrenergic receptor stimulation plays an important role in cardiomyocyte stress responses, which may result in apoptosis and cardiovascular degeneration. We previously demonstrated that toxicity of the β-adrenergic agonist isoproterenol on H9c2 cardiomyoblasts depends on the stage of cell differentiation. We now investigate β-adrenergic receptor downstream signaling pathways and stress responses that explain ...
Sanguinarine cytotoxicity on mouse melanoma K1735-M2 cells--Nuclear vs. mitocho...
Serafim, Teresa L.; Matos, Júlio A.C.; Sardão, Vilma A.; Pereira, Gonçalo C.; Branco, Ana F.; Pereira, Sandro L.; Parke, Donna; Perkins, Edward L.http://www.sciencedirect.com/science/article/B6T4P-4T193YB-5/2/8b89adb1a424a742b294db27ed9982c6
Mitochondrially targeted effects of berberine [Natural Yellow 18, 5,6-dihydro-9...
Pereira, Gonçalo C.; Branco, Ana F.; Matos, Júlio A. C.; Pereira, Sandro L.; Parke, Donna; Perkins, Edward L.; Serafim, Teresa L.; Sardão, Vilma A.Berberine [Natural Yellow 18, 5,6-dihydro-9,10-dimethoxybenzo(g)-1,3-benzodioxolo(5,6-a)quinolizinium] is an alkaloid present in plant extracts and has a history of use in traditional Chinese and Native American medicine. Because of its ability to arrest the cell cycle and cause apoptosis of several malignant cell lines, it has received attention as a potential anticancer therapeutic agent. Previous studies sug...
| Financiadores do RCAAP | |||||||
|
|
|
|
|
|
||