Glioblastoma (GBM) is the most common and aggressive primary brain tumor. The identification of novel molecular prognostic markers of GBM has recently been an area of great interest in neuro-oncology. The methylation status of the MGMT gene promoter is currently a promising molecular prognostic marker, but some controversial data have precluded its clinical use. We analyzed MGMT methylation by methylation-speci...
In this article the authors, basing their arguments on their experience within the framework of initial teacher training of third cycle French teachers in basic and secondary education and their own action-research, discuss the necessity for innovation with regard to the new curricula for initial training of language teachers to be implemented at this institution in the light of the objectives of the Bologna De...
Quatro vacinas inativadas, produzidas com uma amostra do herpesvírus bovino tipo 5 ( BHV-5) isolada de um surto de meningoencefalite no Rio Grande do Sul, foram administradas em quarenta bovinos visando a avaliar a sua capacidade imunogênica. As vacinas A e B foram formuladas com adjuvante oleoso e as vacinas C e D com hidróxido de alumínio [ Al2 (OH)3] . O título da suspensão viral utilizada nas vacinas foi de...
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