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Estrogen metabolism to investigate carcinogenicity of Schistosoma haematobium

Novas moléculas identificadas em doença parasitária estão relacionadas com canc...

Carcinogenic Ability of Schistosoma Haematobium Possibly through Oncogenic Muta...

Schistosoma haematobium is a parasitic flatworm that infects millions of people, mostly in the developing world, and is associated with high incidence of bladder cancer, although why is not clear. Previously, we have used CD-1 mice to show that Schistosoma haematobium total antigen (Sh) has a carcinogenic ability. Sh intravesically instillation induced the development of several urothelial lesions, namely nodul...

Schistosoma haematobium e cancro da bexiga: a verdade escondida

Schistosoma haematobium e cancro da bexiga: a verdade escondida

Idoso que cuida de idosa

Mestrado em Ciências de Enfermagem ; Master Degree in Sciences of Nursing

Schistosoma haematobium and bladder cancer: what lies beneath?

Schistosoma haematobium is a parasitic flatworm that infects millions of people, mostly in the developing world, and is associated with high incidence of bladder cancer although why is not clear. But our group was able to define the mechanistic relationship for the first time between infection of S. haematobium and cancer. We used in vitro models to demonstrate the presence of informative carcinogenesis-associa...

Granulomatous-like immune reaction and hepatic fibrosis induced by Schistosoma ...

Golden hamsters were inoculated with Schistosoma haematobium cercariae to examine histological lesions at different time points over an 18 month period of infection. Hamsters were sacrificed 26 weeks and 82 weeks after inoculation. The parasite was found in the blood and in the liver of infected animals as was expected, but we found exclusively male worms, no female worms nor eggs. Interestingly we observed une...