Encontrados 14 documentos, a visualizar página 1 de 2
Cultura de tecidos de Hypericum foliosum e análise de genes associados à biossí...
Borba, Ana Rita AndradeTese apresentada à Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa para a obtenção do grau de Mestre em Genética Molecular e Biomedicina ; O género Hypericum caracteriza-se pela ocorrência de compostos biologicamente activos com grande importância farmacêutica, nomeadamente as hipericinas. Nos Açores o potencial de plantas endémicas com interesse biotecnológico, como o pequeno arbusto Hyperic...
Molecular Structure, Infrared Spectra, and Photochemistry of Isoniazid under Cr...
Borba, Ana; Gómez-Zavaglia, Andrea; Fausto, RuiIn this study, the structure, spectroscopy, and photochemistry of isoniazid (C6H7N3O, INH) were studied by low-temperature infrared spectroscopy and quantum chemistry calculations. According to DFT(B3LYP)/6-311++G(d,p) calculations, 12 minima were found on the potential energy surface of the molecule, corresponding to two cis conformers about the O═C−N−N axis (C1, C2) and one form trans about this axis (T), all...
Low Temperature Infrared Spectroscopy Study of Pyrazinamide: From the Isolated ...
Borba, Ana; Albrecht, Merwe; Gómez-Zavaglia, Andrea; Suhm, Martin A.; Fausto, RuiA structural and spectroscopic analysis of the anti-tuberculosis drug pyrazinamide (PZA) was carried out. The PZA molecule was predicted theoretically to possess two conformers differing by internal rotation around the C−C(═O) bond, with the E conformer (Cs symmetry point group; N−C−C═O dihedral: 180°) being ca. 30 kJ mol−1 more stable than the Z form (C1 point group; N−C−C═O dihedral: ca. ± 42°). In consonance...
Interaction of nicotinamide and picolinamide with phosphatidylcholine and phosp...
Borba, Ana; Lairion, Fabiana; Disalvo, Anibal; Fausto, RuiInteraction between the bioactive compounds nicotinamide and picolinamide and phospholipids (phosphatidylcholines and phosphatidylethanolamines) was investigated by a combined approach using dipole potential measurements and quantum chemical calculations. It is shown that nicotinamide and picolinamide interactions with phosphatidylcholines are of two main types: (i) specific interactions with the phosphate grou...
Dimer formation in nicotinamide and picolinamide in the gas and condensed phase...
Borba, Ana; Albrecht, Merwe; Gómez-Zavaglia, Andrea; Lapinski, Leszek; Nowak, Maciej J.; Suhm, Martin A.; Fausto, RuiAggregation of nicotinamide (3-pyridine-carboxamide; NA) and picolinamide (2-pyridine-carboxamide; PA) has been investigated by matrix-isolation, supersonic jet and neat solid state infrared spectroscopy, complemented by DFT(B3LYP)/6-311++G(d,p) calculations. For both compounds, the most stable dimeric structure was shown to be the centrosymmetric dimer where two monomers in their most stable forms establish tw...
Potência em equipes : desenvolvimento de uma medida
Borba, Ana Cristina PortmannDissertação (mestrado)—Universidade de Brasília, Instituto de Psicologia, Departamento de Psicologia Social e do Trabalho, Programa de Pós-Graduação em Psicologia Social, do Trabalho e das Organizações, 2007. ; O emprego de equipes de trabalho como unidade de desempenho tem se tornado uma prática cada vez mais freqüente nas organizações modernas. Como conseqüência, emerge a necessidade de conhecer quais são ...
Molecular Structure, Vibrational Spectra, Quantum Chemical Calculations and Pho...
Borba, Ana; Gómez-Zavaglia, Andrea; Fausto, R.Picolinamide (PA) and isonicotinamide (INA), two structural isomers of pyridinecarboxamide, have been investigated by matrix isolation and low-temperature solid-state infrared spectroscopy, combined with UV (λ > 235 nm) photoexcitation and density functional theory and ab initio (MP2) theoretical studies. In consonance with the theoretical data, both PA and INA were found to exist in a single conformation in cr...
Conformational cooling and conformation selective aggregation in dimethyl sulfi...
Borba, Ana; Gómez-Zavaglia, Andrea; Fausto, RuiDimethyl sulfite has three conformers of low energy, GG, GT and GG0, which have significant populations in the gas phase at room temperature. According to theoretical predictions, the GT and GG0 conformers are higher in energy than the GG conformer by 0.83 and 1.18 kJ molK1, respectively, while the barriers associated with the GG0/GT and GT/GG isomerizations are 1.90 and 9.64 kJ molK1, respectively. Experimenta...
Manifestações extrapulmonares da paracoccidioidomicose
Costa,Marlos Augusto Bitencourt; Carvalho,Tarcísio Nunes; Araújo Júnior,Cyrillo Rodrigues de; Borba,Ana Olívia Cardoso; Veloso,Gerson AugustoNeste trabalho os autores realizam um estudo revisional e iconográfico de pacientes portadores da paracoccidioidomicose disseminada, apresentando os principais achados radiográficos no sistema nervoso central, glândulas adrenais, sistema osteoarticular, ganglionar e trato digestivo destes pacientes. Os métodos de diagnóstico por imagem têm permitido uma abordagem mais precisa destes pacientes e se mostrado cada...
Matrix-isolation FT-IR spectra and theoretical study of dimethyl sulfate
Borba, Ana; Gómez-Zavaglia, Andrea; Simões, Pedro N. N. L.; Fausto, RuiThe preferred conformations of dimethyl sulfate and their vibrational spectra were studied by matrix-isolation FT-IR spectroscopy and theoretical methods (DFT and MP2, with basis sets of different sizes, including the quadruple-zeta, aug-cc-pVQZ basis). Conformer GG (of C2 symmetry and exhibiting OSOC dihedral angles of 74.3°) was found to be the most stable conformer in both the gaseous phase and isolated in a...
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