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Unveiling the Interaction of Vanadium Compounds with Human Serum Albumin by Usi...
Dias, David M.; Rodrigues, João P. G. L. M.; Domingues, Neuza S.; Bonvin, Alexandre M. J. J.; Castro, M. M. C. A.The binding of the VV oxidation products of two vanadium( IV) compounds, [VO(dmpp)2] and [VO(maltolato)2], which have shown promising anti-diabetic properties, to human serum albumin (HSA) in aqueous aerobic solution has been studied by 1H saturation transfer difference (STD) NMR spectroscopy and computational docking studies. Group epitope mapping and docking simulations indicate a preference of HSA binding to...
Data: 2013
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Origem: Estudo Geral - Universidade de Coimbra
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