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Degradation studies of hydrophilic, partially degradable and bioactive cements ...

Micropatterning of bioactive glass nanoparticles on chitosan membranes for spat...

Bioactive glass nanoparticles (BG-NPs) capable of inducing apatite precipitation upon immersion in simulated body fluid (SBF) were patterned on free-standing chitosan membranes by microcontact printing using a poly(dimethylsiloxane) (PDMS) stamp inked in a BG-NPs pad. Formation of the patterns was characterized by scanning electron microscopy (SEM). Mineralization of the bioactive glass patterns was induced in ...

Micropatterning of bioactive glass nanoparticles on chitosan membranes for spat...

Innovative approach for producing injectable, biodegradable materials using chi...

Although there are a number of injectable biomaterials currently under development, they present some drawbacks such as being based on synthetic polymers, needing toxic or aggressive synthesis procedures or using raw materials with low availability and/or high production costs. Having this in mind, a novel injectable biomaterial using chitooligosaccharides as starting materials was developed. This system uses a...

Melt-based compression-molded scaffolds from chitosan-polyester blends and comp...

Blends of chitosan and synthetic aliphatic polyesters (polybutylene succinate, polybutylene succinate adipate, polycaprolactone, and polybutylene terepthalate adipate) were compounded with and without hydroxyapatite, a bioactive mineral filler known to enhance osteoconduction. The blends and composites were compression molded with two different granulometric salt sizes (63–125 lm and 250–500 lm) having differen...

A review on the polymer properties of hydrophilic, partially degradable and bio...

Acrylic bone cements were developed around 50 years ago for the fixation of hip prostheses during arthroplasty. Over the intervening years, a series of drawbacks have been disclosed that have fostered intensive research on the development of novel or alternative formulations to the standard acrylic cements. Here, we will review the development and characterization of a novel class of cements, the Hydrophilic, p...

The in vitro bioactivity of two novel hydrophilic, partially degradable bone ce...

Composite bone cements were prepared with bioactive glasses (MgO–SiO2–3CaO Æ P2O5) of different reactivities. The matrix of these so-called hydrophilic, partially degradable and bioactive cements was composed of a starch/cellulose acetate blend and poly(2-hydroxyethyl methacrylate). The addition of 30 wt.% of glasses to this system made them bioactive in acellular medium: a dense apatite layer formed on the sur...

Natural origin biodegradable systems in tissue engineering and regenerative med...

The fields of tissue engineering and regenerative medicine aim at promoting the regeneration of tissues or replacing failing or malfunctioning organs, by means of combining a scaffold/support material, adequate cells and bioactive molecules. Different materials have been proposed to be used as both three-dimensional porous scaffolds and hydrogel matrices for distinct tissue engineering strategies. Among them, p...

Incorporation of alpha-amylase enzyme and a bioactive filler into hydrophilic, ...

Hydrophilic, partially degradable, and bioactive cements (HDBCs) are starch-containing cements intended to degrade partially in the human body and, in so doing, allow for bone ingrowth inside the pores formed during degradation. Therefore, the study of degradation and bioactivity behavior was performed to assess the suitability of the current HDBCs formulations to achieve those aims. The degradation profile of ...

The effect of water uptake on the behaviour of hydrophilic cements in confined ...

Physiological fluids will be in contact with the implant components from the first moments after a surgery. Therefore, the study of the effect of water on the properties of the bone cements that are part of the arthroplasty procedure is of critical importance to predict the long-term performance of the whole system. In our research group, we have developed a novel concept, the hydrophilic, partially degradable ...