Encontrados 6 documentos, a visualizar página 1 de 1
Nanostructured 3D constructs based on chitosan and chondroitin sulphate multila...
Silva, Joana M.; Georgi, N.; Costa, Rui; Praveen, S.; Reis, R. L.; Blitterswijk, C. A. van; Karperien, M.; Mano, J. F.Nanostructured three-dimensional constructs combining layer-by-layer technology (LbL) and template leaching were processed and evaluated as possible support structures for cartilage tissue engineering. Multilayered constructs were formed by depositing the polyelectrolytes chitosan (CHT) and chondroitin sulphate (CS) on either bidimensional glass surfaces or 3D packet of paraffin spheres. 2D CHT/CS multi-layered...
Wettability influences cell behavior on superhydrophobic surfaces with differen...
Lourenço, Bianca do Nascimento; Marchioli, Giulia; Welong Song; Reis, R. L.; Blitterswijk, C. A. van; Karperien, Marcel; Apeldoorn, Aart van"Published online: 26 July 2012" ; Surface wettability and topography are recognized as critical factors influencing cell behavior on biomaterials. So far only few works have reported cell responses on surfaces exhibiting extreme wettability in combination with surface topography. The goal of this work is to study whether cell behavior on superhydrophobic surfaces is influenced by surface topography and polyme...
Chitosan/Poly(ε-caprolactone) blend scaffolds for cartilage repair
Neves, S. C.; Teixeira, L. S. Moreira; Moroni, L.; Reis, R. L.; Blitterswijk, C. A. van; Alves, N. M.; Karperien, M.; Mano, J. F.Chitosan (CHT)/poly(ε-caprolactone) (PCL) blend 3D fiber-mesh scaffolds were studied as possible support structures for articular cartilage tissue (ACT) repair. Micro-fibers were obtained by wet-spinning of three different polymeric solutions: 100:0 (100CHT), 75:25 (75CHT) and 50:50 (50CHT) wt.% CHT/PCL, using a common solvent solution of 100 vol.% of formic acid. Scanning electron microscopy (SEM) analysis sho...
Evaluation of two biodegradable polymeric systems as substrates for bone tissue...
Mendes, S. C.; Bezemer, J.; Claase, M. B.; Gripma, D. W.; Bellia, G.; Innocenti, F. D.; Reis, R. L.; Groot, K. de; Blitterswijk, C. A. vanThe aim of this study was to evaluate two biodegradable polymeric systems as scaffolds for bone tissue engineering. Rat bone marrow cells were seeded and cultured for 1 week on two biodegradable porous polymeric systems, one composed of poly(ethylene glycol)-terephthalate/poly(butylene terephthalate) (PEGT/PBT) and the other composed of cornstarch blended with poly(ε-caprolactone) (SPCL). Porous hydroxyapatite ...
Cytocompatibility and response of osteoblastic-like cells to starch-based polym...
Gomes, Manuela E.; Reis, R. L.; Cunha, A. M.; Blitterswijk, C. A. van; Bruijn, J. D. deThis work reports on the biocompatibility evaluation of new biodegradable starch-based polymers that are under consideration for use in orthopaedic temporary applications and as tissue engineering scaffolds. It has been shown in previous works that by using these polymers it is both possible to produce polymer/hydroxyapatite (HA) composites (with or without the use of coupling agents) with mechanical properties...
Cytocompatibility and response of osteoblastic-like cells to starch-based polym...
Gomes, Manuela E.; Reis, R. L.; Cunha, A. M.; Blitterswijk, C. A. van; Bruijn, J. D. deThis work reports on the biocompatibility evaluation of new biodegradable starch-based polymers that are under consideration for use in orthopaedic temporary applications and as tissue engineering sca!olds. It has been shown in previous works that by using these polymers it is both possible to produce polymer/hydroxyapatite (HA) composites (with or without the use of coupling agents) with mechanical properties ...
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