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Platelet serotonin as a biological marker of autism.

Platelet levels of serotonin were determined by a quantitative direct radioimmunoassay, in a group of autistic patients and a control group. Thirty six autistic patients (28 males and 8 females), all with severe mental retardation, and a group of 23 matched controls, were studied. The serotonin levels in autistic patients (mean +/- SD) (88.37 mmol/dl +/- 40.38) were significantly higher that in the control grou...

Reduced and oxidized glutathione of the placenta in pregnancy complicated by pr...

Significative enhancement of free radical formation (FRO) in vivo is an important feature of hypertensive disorders of pregnancy (HDP), namely preeclampsia (PIH). The latest investigations about the pathology of HDP, showed the contribution of placental circulation to the development and evolution of such disease. The placental bed can be a potential source of FRO or activation of cells that can produce FRO. Gl...

Erythrocytic enzymatic systems and their antioxidative potential in pregnant wo...

Our purpose is to correlate, the apgar score of the new-borns from induction of labour (IL) with Prostaglandin E2 (PGE2) endocervical gel, and the oxidative environment of the pregnant woman during labour, studying biochemical markers of the erythrocytes. PGE2 is responsible for the regulation of the vascular response in pregnancy, namely for the vasoconstriction caused by Angitensin II. The production of Prost...

Endocrine arterial hypertension. Pheochromocytoma.

The authors emphasize some embryologic features of the chromaffin tissue as a basis of understanding of both the physiopathologic and clinical aspects of Pheochromocytoma. The appropriate sequence of diagnostic procedures was established in order to obtain clinical, biochemical and anatomical evidence of the tumor. It was concluded that an early diagnosis is mandatory in order to plan a curative surgical therap...

Pheochromocytoma. Various genetic aspects.