Encontrados 12 documentos, a visualizar página 1 de 2
On the relevance of the 3D retinal vascular network from OCT data
Serranho, Pedro; Guimarães, P.; Rodrigues, P.; Bernardes, RuiAbnormal patterns of the retinal vascular system have been associated with several heart and cerebral diseases. However, these correlations were obtained using 2D imaging of the eye fundus, disregarding information on the third component (depth) of the vascular system. In this paper, we show that the depth component is relevant and should not be disregarded in this analysis. In this way, the relevance of the an...
Optical coherence tomography: a concept review
Serranho, Pedro; Morgado, António Miguel; Bernardes, RuiOptical coherence tomography (OCT) is an imaging modality broadly used in biologial tissue imaging. In this chapte, we review the history of OCT and its development throughout the last years.
Optical coherence tomography: automatic retina classification through support v...
Bernardes, Rui; Serranho, Pedro; Santos, Torcato; Gonçalves, Valter; Cunha-Vaz, JoséOptical coherence tomography (OCT) is becoming one of the most important imaging modalities in ophthalmology due to its non-invasiveness and by allowing the visualisation the human retina structure in detail. It was recently proposed that OCT data embeds functional information from the human retina. Specifically, it was proposed that blood–retinal barrier status information is present within OCT data from the h...
Synthtic OCT Data for image processing performance testing
Serranho, Pedro; Maduro, Cristina; Santos, Torcato; Vaz, José Cunha; Bernardes, RuiThe use of synthetic images is needed for testing the performance of image processing methods in order to establish a ground truth to test performance metrics. However, these synthetic images do not represent real applications. The aim of this paper is to build a mathematical model to obtain a synthetic noise-free image mimicking a real Optical Coherence Tomography (OCT) B-scan or volume from the human retina, ...
Ocular fundus Imaging: from structure to function
Serranho, Pedro; Maduro, Cristina; Santos, Torcato; Bernardes, Rui; Vaz, José Cunha; Araújo, Adérito; Barbeiro, SílviaImaging the ocular fundus, namely the retina, to detect and/or monitor changes over time from the healthy condition is of fundamental importance to assess onset and disease progression and is a valuable tool to understand the basic mechanisms of ocular diseases. Current trends point to the need for less or non-invasive approaches, to the need for detailed (higher spatial and temporal resolution) imaging systems...
Noninvasive evaluation of retinal leakage using optical coherence tomography
Bernardes, Rui; Santos, Torcato; Serranho, Pedro; Lobo, Conceição; Cunha-Vaz, JoséPurpose: To demonstrate the association between changes in the blood-retinal barrier (BRB) identified by fluorescein leakage and those in the optical properties of the human retina determined by optical coherence tomography (OCT) and show how these changes can be quantified and their location identified within the retina. Methods: Two imaging techniques were applied: the retinal leakage analyzer, to map BRB fun...
Digital ocular fundus imaging: a review
Bernardes, Rui; Serranho, Pedro; Lobo, ConceiçãoOcular fundus imaging plays a key role in monitoring the health status of the human eye. Currently, a large number of imaging modalities allow the assessment and/or quantification of ocular changes from a healthy status. This review focuses on the main digital fundus imaging modality, color fundus photography, with a brief overview of complementary techniques, such as fluorescein angiography. While focusing on ...
Improved adaptive complex diffusion despeckling filter
Bernardes, Rui; Maduro, Cristina; Serranho, Pedro; Araújo, Adérito; Barbeiro, Sílvia; Cunha-Vaz, JoséDespeckling optical coherence tomograms from the human retina is a fundamental step to a better diagnosis or as a preprocessing stage for retinal layer segmentation. Both of these applications are particularly important in monitoring the progression of retinal disorders. In this study we propose a new formulation for a well-known nonlinear complex diffusion filter. A regularization factor is now made to be depe...
Desenvolvimento de novas metodologias para o mapeamento multimodal da mácula
Bernardes, Rui Manuel Dias Cortesão dos SantosTese de doutoramento em Ciências da Saúde - Ciências Biomédicas apresentada à Faculdade de Medicina de Coimbra
Nonproliferative retinopathy in diabetes type 2. Initial stages and characteriz...
Cunha-Vaz, José; Bernardes, RuiThis review addresses the initial stages of nonproliferative diabetic retinopathy in diabetes type 2. ; http://www.sciencedirect.com/science/article/B6TBT-4F1W6T6-1/1/dec451a0b9d54c244324296ec9426f6e
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