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Anti-inflammatory activity of Cymbopogon citratus leaves infusion via proteasom...
Francisco, Vera; Costa, Gustavo; Figueirinha, Artur; Marques, Carla; Pereira, Paulo; Neves, Bruno Miguel; Lopes, Maria Celeste; García-Rodríguez, CarmenEthnopharmacological relevance Cymbopogon citratus (DC.) Stapf leaves infusion is used in traditional medicine for the treatment of inflammatory conditions, however little is known about their bioactive compounds. Aim of the study Investigate the compounds responsible for anti-inflammatory potential of Cymbopogon citratus (Cy) on cytokines production induced by lipopolysaccharide (LPS) in human and mouse macro...
Cymbopogon citratus as source of new and safe anti-inflammatory drugs: Bio-guid...
Francisco, Vera; Figueirinha, Artur; Neves, Bruno Miguel; García-Rodríguez, Carmen; Lopes, Maria Celeste; Cruz, Maria Teresa; Batista, Maria TeresaEthnopharmacological relevance Aqueous extracts of Cymbopogon citratus (Cy) leaves are used in traditional medicine for the treatment of inflammatory conditions, however, little is known about their mechanism of action. Aim of the study The aim of this study is to explore the anti-inflammatory properties of Cymbopogon citratus leaves and their polyphenol-rich fractions (PFs), as well its mechanism of action i...
Neuropharmacological evaluation of the putative anxiolytic effects of Passiflor...
Coleta, Miguel; Batista, Maria Teresa; Campos, Maria Graça; Carvalho, Rui; Cotrim, Maria Dulce; Lima, Thereza Christina M. de; Cunha, António Proença daPassiflora edulis Sims together with several other plants of the genus Passiflora have been reported to possess anxiolytic properties. It has been suggested recently that flavonoids may be partly responsible for the neuropharmacological activity of these plants but there are still few data reporting the relation between the constituents of these plants and their activity. This work evaluated the anxiolytic/seda...
Polyphenolic profile characterization of Agrimonia eupatoria L. by HPLC with di...
Correia, Helena; González-Paramás, Ana; Amaral, Maria Teresa; Santos-Buelga, Celestino; Batista, Maria TeresaLiquid chromatography coupled to diode array and electrospray ionization mass spectrometry detection was used to establish the polyphenolic profile of an ethyl acetate fraction from Agrimonia eupatoria L. aqueous-alcoholic extract. Additionally, an HPLC technique with post-column derivatization by p-dimethylaminocinnamaldehyde was employed for the selective detection and quantification of flavan-3-ols. Importan...
Antioxidant properties of proanthocyanidins of Uncaria tomentosa bark decoction...
Gonçalves, Cristina; Dinis, Teresa; Batista, Maria TeresaDecoctions prepared from the bark of Uncaria tomentosa (cat's claw) are widely used in the traditional Peruvian medicine for the treatment of several diseases, in particular as a potent anti-inflammatory agent. Therefore, the main purpose of this study was to determine if the well-known anti-inflammatory activity of cat's claw decoction was related with its reactivity with the oxidant species generated in the i...
Characterisation of polyphenols by HPLC-PAD-ESI/MS and antioxidant activity in ...
Correia, Helena; González-Paramás, Ana; Amaral, Maria Teresa; Santos-Buelga, Celestino; Batista, Maria TeresaThe antioxidant activity of an aqueous extract (infusion) and respective ethyl acetate fraction of Equisetum telmateia Ehrh. (Equisetaceae), a plant used in traditional medicine for its anti-inflammatory and diuretic properties, has been evaluated by DPPH, TEAC and TBARS assays. A high and significant antioxidant activity was detected in the ethyl acetate fraction. Analysis of the aqueous extract and the ethyl ...
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