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Cellular hypomethylation is associated with impaired nitric oxide production by...

Hyperhomocysteinemia (HHcy) is a risk factor for vascular disease, but the underlying mechanisms remain incompletely defined. Reduced bioavailability of nitric oxide (NO) is a principal manifestation of underlying endothelial dysfunction, which is an initial event in vascular disease. Inhibition of cellular methylation reactions by S-adenosylhomocysteine (AdoHcy), which accumulates during HHcy, has been suggest...

Forecasting the risk of WRMSDs in home care nurses

Studies regarding work related musculoskeletal disorders (WRMSDs) in nurses have been carried out mostly in hospitals or in other institutional contexts. Information about this theme in providing home-based care is scarce. The main goals of this work are the characterization of musculoskeletal complaints in nurses who work at the Health Centers of the northern Portugal and that provide home-based care, the iden...

Musculoskeletal disorders in nurses : hospital versus home care

DNA-based biosensor for the electrocatalytic determination of antioxidant capac...

Reactive oxygen species (ROS) are produced as a consequence of normal aerobic metabolism and are able to induce DNA oxidative damage. At the cellular level, the evaluation of the protective effect of antioxidants can be achieved by examining the integrity of the DNA nucleobases using electrochemical techniques. Herein, the use of an adenine-rich oligonucleotide (dA21) adsorbed on carbon paste electrodes for the...

Towards a reliable technology for antioxidant capacity and oxidative damage eva...

To counteract and prevent the deleterious effect of free radicals the living organisms have developed complex endogenous and exogenous antioxidant systems. Several analytical methodologies have been proposed in order to quantify antioxidants in food, beverages and biological fluids. This paper revises the electroanalytical approaches developed for the assessment of the total or individual antioxidant capacity. ...

Alteração do comprimento do passo durante a transposição de obstáculos em taref...

A Construção Civil tem sido o sector que regista maior incidência de acidentes fatais a nível mundial. Diversos estudos têm sido efectuados no sentido de compreender as causas que contribuem para a ocorrência de elevados índices de sinistralidade neste sector. Todavia, o contributo da movimentação manual de cargas, para a ocorrência de quedas na Construção Civil, tem sido descurado. No presente artigo procedeu...

Musculoskeletal complaints in nurses who provide home-based healthcare

Work related musculoskeletal disorders (WRMSDs) have been described as the major occupational health problem affecting nurses. Main goals of this work are the characterization and evaluation of musculoskeletal complaints in nurses who work at Health Centres at the Northern Portugal and that provide home-based care. This work demonstrates an analysis of the responses to a questionnaire based on one other develop...

Gold electrode modified by self-assembled monolayers of thiols to determine DNA...

The process of immobilization of biological molecules is one of the most important steps in the construction of a biosensor. In the case of DNA, the way it exposes its bases can result in electrochemical signals to acceptable levels. The use of self-assembled monolayer that allows a connection to the gold thiol group and DNA binding to an aldehydic ligand resulted in the possibility of determining DNA hybridiza...

Musculoskeletal disorders in nurses who provide home care

Work related musculoskeletal disorders (WRMSDs) have been described as the most important occupational health problem tormenting the nursing workers. This work demonstrated a preliminary analysis on the evaluation of responses to a questionnaire based on one developed by Kuorinka and colleagues. Main goal of this work is the characterisation and evaluation of the risk of WRMSDs on the home care nursing. The fir...

Survey of trace elements (Al, As, Cd, Cr, Co, Hg, Mn, Ni, Pb, Se, and Si) in re...

Concentrations of eleven trace elements (Al, As, Cd, Cr, Co, Hg, Mn, Ni, Pb, Se, and Si) were measured in 39 (natural and flavoured) water samples. Determinations were performed using graphite furnace electrothermetry for almost all elements (Al, As, Cd, Cr, Co, Mn, Ni, Pb, and Si). For Se determination hydride generation was used, and cold vapour generation for Hg. These techniques were coupled to atomic absor...