As migrações e a globalização dos viajantes têm apresentado grandes desafios no controlo da transmissão de doenças. Em 2012, o número estimado de pessoas em risco de contraíram malária foi de 3,4 biliões. Na Europa, esta é uma doença rara que, em 2012, apenas teve reportados 255 casos autóctones. Para turistas e emigrantes de áreas não endémicas, a malária representa um sério risco de morte e deve ser uma forte...
INTRODUCTION: Portugal is the European country with the highest frequency of HIV-2 infection, which is mainly concentrated in West Africa. The cumulative number of notified HIV-2 infections in Portugal was 1813 by the end of December 2008. To better characterize the dynamics of HIV-2 infection in the country and to obtain data that may be of use in the prevention of the spread of HIV-2, we evaluated a large poo...
Female rats are intensely affected by cocaine, with estrogen probably playing an important role in this effect. Progesterone modulates the GABA system and attenuates the effects of cocaine; however, there is no information about its relevance in changing GABA synthesis pathways after cocaine administration to female rats. Our objective was to investigate the influence of progesterone on the effects of repeated ...
Caracterização das áreas amostradas; Amostragem dos espécimes de moscas-das-frutas; Identificação das espécies de moscas-das-frutas e seus parasitóides; Identificação específica das plantas hospedeiras; Caracterização e delimitação das populações de moscas-das-frutas; Flutuação populacional das moscas-das-frutas; Moscas-das-frutas capturadas com armadilhas McPhail; Moscas-das-frutas obtidas das amostras de frut...
The objective of the present study was to determine if the acute behavioral effects of cocaine acutely administered intraperitoneally (ip) at doses of 5, 10 and 20 mg/kg on white male CF1 mice, 90 days of age, would be influenced by leptin acutely administered ip (at doses of 5, 10 and 20 µg/kg) or by endogenous leptin production enhanced by a high-fat diet. The acute behavioral effects of cocaine were evaluate...
Public Health. 2005 Jul;119(7):587-9. Self-reported food and drug allergy in Maputo, Mozambique. Lunet N, Falcão H, Sousa M, Bay N, Barros H. SourceDepartment of Hygiene and Epidemiology, University of Porto Medical School, Portugal. nlunet@med.up.pt PMID: 15925673 [PubMed - indexed for MEDLINE]
In experimental ageing models an inverse relationship between age and alkaline phosphatase activity has been observed.To characterize serum levels of alkaline phosphatase activity in humans according to age and gender.Serum alkaline phosphatase was determined in a random sample of 203 community dwellers aged 40 or more years.In men (n=87) total serum alkaline phosphatase markedly increased from the 5th to the 6...
Pilocarpine is a cholinergic agonist that increases salivary flow and has been used to treat xerostomia. Oral intake is the most frequent route of administration. Adverse effects are dose-dependent and include sudoresis, facial blushing and increased urinary frequency. The objective of the present study was to evaluate the effects of topical pilocarpine solutions as mouthwashes on salivary flow and their advers...
Diabetic patients have a 20% higher risk of depression than the general population. Treatment with antidepressant drugs can directly interfere with blood glucose levels or may interact with hypoglycemic agents. The treatment of depression in diabetic patients must take into account variations of glycemic levels at different times and a comparison of the available antidepressant agents is important. In the prese...
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