Encontrados 17 documentos, a visualizar página 1 de 2
Potencial biotecnológico do mar dos Açores
Barreto, Maria do Carmo; Seca, Ana M. L.; Costa, Ana C.; Neto, Ana I.; Simões, NelsonO ambiente marinho constitui uma extraordinária reserva de compostos com caracterÃsticas estruturais únicas, diferentes das encontradas nos Produtos Naturais de origem terrestre. Os compostos de origem marinha assumem assim um papel cada vez mais significativo na descoberta de novos medicamentos, de novas aplicações em cosmética, na produção de enzimas com caracterÃsticas especÃficas ou como biomateri...
Xanthenedione derivatives, new promising antioxidant and acetylcholinesterase i...
Seca, Ana M. L.; Leal, Stephanie B.; Pinto, Diana C. G. A.; Barreto, Maria do Carmo; Silva, Artur M. S.Natural and synthetic xanthone derivatives are well-known for their ability to act as antioxidants and/or enzyme inhibitors. This paper aims to present a successful synthetic methodology towards xanthenedione derivatives and the study of their aromatization to xanthones. Additionally their ability to reduce Fe(III), to scavenge DPPH radicals and to inhibit AChE was evaluated. The results demonstrated that xanth...
Chemical study and biological activity evaluation of two Azorean Macroalgae: Ul...
Silva, Madalena; Vieira, Luís M.; Almeida, Ana Paula; Silva, Artur M. S.; Seca, Ana M. L.; Barreto, Maria do Carmo; Neto, Ana I.; Pedro, MadalenaCopyright: © 2013 Silva M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credite. ; The green macroalga Ulva rigida C. Agardh (Chlorophyta) and the red macroalga Gelidium microdon Kützing (Rhodophyta), collected from the Azore...
Valuable compounds on conifers, macroalgae and halophyte species
Isca, Vera M. S.; Gouveia, Vera F.; Seca, Ana M. L.; Barreto, Maria do Carmo; Pinto, Diana C. G. A.; Silva, Artur M. S.; Kijjoa, AnakeXXIII Encontro Nacional da Sociedade Portuguesa de Química, Aveiro 12 a 14 de Junho de 2013. ; As part of our on-going investigation on bioactive secondary metabolites, we carried out the phytochemical study of the endemic conifer Juniperus brevifolia and the macroalga Cystoseira abies-marine from Azores Islands, and also of the halophyte Salicornia ramosissima from Aveiro lagoon. This communication gives an o...
Cytotoxic, antibacterial, antioxidant, and anticholinesterasic activity of Juni...
Oliveira, Nemésia; Medeiros, Sofia; Barreto, Maria do Carmo; Seca, Ana M. L.; Rosa, José S.XXIII Encontro Nacional da Sociedade Portuguesa de Química. Aveiro, 12-14 de Junho 2013. ; The cytotoxic, antibacterial, antioxidant and anticholinesterasic (anti-AChE) activities of the methanol and acetone extracts of Juniperus brevifolia wood and bark were determined. The present study demonstrates that bark extracts of J. brevifolia are the most active and showed good antioxidant activity, lower anti-AChE ...
A natureza sob o olhar da química: caracterizaçao de novas moléculas activas is...
Lima, Elisabeth; Baptista, José; Medeiros, João; Barreto, Maria do Carmo; Neto, Ana I.; Paiva, Lisete S.; Patarra, Rita F.Jornadas "Ciência nos Açores – que futuro?", Ponta Delgada, 7-8 de Junho de 2013. ; A área de Química de Produtos Naturais tem contribuído, grandemente, para a descoberta de fármacos e agroquímicos, entre outros, por meio do isolamento de substâncias ativas produzidas por diversos organismos. As novas moléculas têm grande interesse científico, económico, social e farmacológico podendo contribuir, em muito, par...
Macroalgae from S. Miguel Island as a potential source of antiproliferative and...
Barreto, Maria do Carmo; Mendonça, Emanuel A.; Gouveia, Vera F.; Anjos, Carolina; Medeiros, Joana S.; Seca, Ana M. L.; Neto, Ana I.Ulva compressa, Gelidium microdon, Osmundea pinnatifida, Fucus spiralis and Cystoseira abies-marina from the coast of S. Miguel Island were screened for their in vitro cytotoxicity against HeLa tumour cell line, antioxidant potential and total phenolic content. From each alga, the hexane fraction (HF) of the methanol extract, the methanol residue (MF) and the dichloromethane extract (DE), were obtained and eval...
Bioactive meroditerpenes from Cystoseira abies-marina, collected from the coast...
Gouveia, Vera L. M.; Seca, Ana M. L.; Barreto, Maria do Carmo; Silva, Artur M. S.; Kijjoa, Anake3rd Portuguese Meeting on Medicinal Chemistry and 1st Portuguese-Spanish-Brazilian Meeting on Medicinal Chemistry, Aveiro, 28-30 Novembro 2012. ; Many substances isolated from marine organisms have demonstrated to possess interesting biological and pharmacological activities and have been used as leads in the development of new pharmaceutical agents. Marine macroalgae are abundant and structuring organisms of ...
Chemical and biological studies from an Azorean macroalga: Ulva rigida
Silva, Madalena; Vieira, Luís M. M.; Almeida, Ana Paula; Silva, Artur M. S.; Kijjoa, Anake; Seca, Ana M. L.; Barreto, Maria do Carmo3rd Portuguese Meeting on Medicinal Chemistry and 1st Portuguese-Spanish-Brazilian Meeting on Medicinal Chemistry, Aveiro, 28-30 Novembro 2012. ; New drugs from natural sources have been targets of the drug discovery program and some bioactive compounds from macroalgae such as sulfated polysaccharides, steroids and diterpens have found their applications in the pharmaceutical industry.[1,2] Consequently, we ha...
Purification and structural characterization of compounds isolated from Cystose...
Gouveia, Vera L. M.; Seca, Ana M. L.; Barreto, Maria do Carmo; Silva, Artur M. S.; Kijjoa, Anake6th Spanish-Portuguese-Japanese Organic Chemistry Symposium, Lisboa, de 18 a 20 de Julho de 2012 (Poster Communication). ; Although the Azores archipelago is rich in algal communities, only two papers have been published concerning the nutritional and pharmacological potential of this resource in the Azorean sea.[4,5,6] As a brown alga Cystoseira abies-marina grows abundantly in the coast of these islands and ...
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