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Dysfunction of the Heteromeric KV7.3/KV7.5 Potassium Channel is Associated with...

Gilling, M.; Rasmussen, H.B.; Calloe, K.; Sequeira, A.F.; Barreto, M.; Oliveira, G.; Almeida, J.; Lauritsen, M.B.; Ullmann, R.; Boonen, S.E.

Heterozygous mutations in the KCNQ3 gene on chromosome 8q24 encoding the voltage-gated potassium channel KV7.3 subunit have previously been associated with rolandic epilepsy and idiopathic generalized epilepsy (IGE) including benign neonatal convulsions. We identified a de novo t(3;8) (q21;q24) translocation truncating KCNQ3 in a boy with childhood autism. In addition, we identified a c.1720C > T [p.P574S] nucl...


Compensatory T-Cell Regulation in Unaffected Relatives of SLE Patients, and Opp...

Fesel, C.; Barreto, M.; Ferreira, R.C.; Costa, N.; Venda, L.L.; Pereira, C.; Carvalho, C.; Morães-Fontes, M.F.; Ferreira, C.M.; Vasconcelos, C.

In human systemic lupus erythematosus (SLE), diverse autoantibodies accumulate over years before disease manifestation. Unaffected relatives of SLE patients frequently share a sustained production of autoantibodies with indiscriminable specificity, usually without ever acquiring the disease. We studied relations of IgG autoantibody profiles and peripheral blood activated regulatory T-cells (aTregs), represented...


Distribuição espacial de Phytophthora nicotianae e reação de cultivares de cebo...

Almeida,F.A.; Barreto,M.; Barbosa,J.C.; Costa,F.M.

A cultura da cebola vem se mostrando altamente suscetível ao ataque de Phytophthora nicotianae, com danos econômicos e alto custo de produção pelo uso excessivo de produtos químicos. O presente trabalho teve como objetivo avaliar a dependência espacial do patógeno por meio da Geoestatística e em seguida, testar a resistência de cultivares de cebola sob sistema convencional de cultivo ao fungo. Os experimentos f...

Data: 2011   |   Origem: OASIS br

Detection of caliciviruses associated with acute infantile gastroenteritis in S...

Xavier,M.P.T.P.; Oliveira,S.A.; Ferreira,M.S.R.; Victoria,M.; Miranda,V.; Silva,M.F.M.; Strina,A.; Barreto,M.L.; Miagostovicht,M.P.; Leite,J.P.G.

Acute gastroenteritis caused by viruses is one of the leading causes of infantile morbidity. The aim of the present study was to investigate the presence of human caliciviruses of the genera norovirus and sapovirus in children up to 3 years of age with acute gastroenteritis from low-income communities in the city of Salvador, Brazil. This study is an extension of previous work carried out to establish the profi...

Data: 2009   |   Origem: OASIS br

Low frequency of CD4+CD25+ Treg in SLE patients: a heritable trait associated w...

Barreto, M.; Ferreira, R.; Lourenço, L.; Moraes-Fontes, M.; Santos, E.; Alves, M.; Carvalho, C.; Martins, B.; Andreia, R.; Viana, J.; Vasconcelos, C.

Abstract BACKGROUND: CD4+CD25+ regulatory T cells play an essential role in maintaining immune homeostasis and preventing autoimmunity. Therefore, defects in Treg development, maintenance or function have been associated with several human autoimmune diseases including Systemic Lupus Erythematosus (SLE), a systemic autoimmune disease characterized by loss of tolerance to nuclear components and significantly mor...


Low frequency of CD4+CD25+ Treg in SLE patients: a heritable trait associated w...

Barreto, M.; Ferreira, R.C.; Lourenço, L.; Moraes-Fontes, M.F.; Santos, E.; Alves, M.; Carvalho, C.; Martins, B.; Andreia, R.; Viana, J.F.

CD4+CD25+ regulatory T cells play an essential role in maintaining immune homeostasis and preventing autoimmunity. Therefore, defects in Treg development, maintenance or function have been associated with several human autoimmune diseases including Systemic Lupus Erythematosus (SLE), a systemic autoimmune disease characterized by loss of tolerance to nuclear components and significantly more frequent in females...


Caracterização das bases de produção orgância no Rio Grande do Norte.

CUENCA, M. A. G.; MOREIRA, M. A. B.; NUNES, M. U. C.; MATA, S. S. da; GUES, C. G. M.; BARRETO, M. de F. P.; LOPES, V. R. M.; PAZ, F. das C. A.

2007

Data: 2007   |   Origem: OASIS br

Perfil do consumidor e do consumo de produtos orgânicos no Rio Grande do Norte.

CUENCA, M. A. G.; MOREIRA, M. A. B.; NUNES, M. U. C.; MATA, S. S. da; GUES, C. G. M.; BARRETO, M. de F. P.; LOPES, V. R. M.; PAZ, F. das C. A.

2007

Data: 2007   |   Origem: OASIS br

Low frequency of CD4(+) CD25(+) Treg in SLE patients: a heritable trait associa...

Barreto, M.; Ferreira, RC.; Lourenço, L.; Moraes-Fontes, MF.; Santos, E.; Alves, M.; Carvalho, C.; Martins, B.; Andreia, R.; Viana, JF.; Vasconcelos, C.

Background: CD4(+)CD25(+) regulatory T cells play an essential role in maintaining immune homeostasis and preventing autoimmunity. Therefore, defects in Treg development, maintenance or function have been associated with several human autoimmune diseases including Systemic Lupus Erythematosus (SLE), a systemic autoimmune disease characterized by loss of tolerance to nuclear components and significantly more fre...


Accurate Gaussian basis sets for the ground state of the CS molecule

Barreto,M. T.; Muniz,E. P.; Jorge,F. E.; Centoducatte,R.

Sequences of increasing size atom centered basis sets of Gaussian-type functions for the ground state of the CS molecule are generated with the molecular improved generator coordinate Hartree-Fock (HF) method. At the HF level, total and orbital energies and electric dipole moment and, at the second-order Mphiller-Plesset (MP2) level, correlation and dissociation energies and electric dipole moment were calculat...

Data: 2005   |   Origem: OASIS br

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    Financiadores do RCAAP

Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia