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Interaction of DODAB with neutral phospholipids and cholesterol studied using f...

Liposomes composed of cationic lipids and neutral phospholipids have been used as vehicles for cellular delivery of DNA and drug delivery. The aim of this study is to get a better understanding of phospholipid–cationic lipid interactions that is essential for the development of this potential. We have studied the interaction between cationic lipid liposomes primarily composed of dioctadecyldimethylammonium brom...

Domain formation in DODAB–cholesterol mixed systems monitored via nile red anis...

The effect of the cholesterol (Ch) on liposomes composed of the cationic lipid dioctadecyldimethylammonium bromide (DODAB) was assessed by studying both the steady-state and time-resolved fluorescence anisotropy of the dye Nile Red. The information obtained combined with analysis of the steady-state emission and luorescence lifetime of Nile Red (NR) for different cholesterol concentrations (5–50%) elucidated t...

Fluorescence studies of the interaction of pyrenylmethyl tributylphosphonium br...

The interaction between pyren-1-ylmethyl tri-n-butylphosphonium bromide (PMTP), a water-soluble cationic pyrene derivative and the double-strand polynucleotides Poly[dA-dT], Poly[dA].Poly[dT], Poly[dG-dC] and Poly[dG]. Poly[dC] was studied using UV-Vis absorption and fluorescence spectroscopy. The PMTP probe interacts with polynucleotides through both weak and intercalative binding, evidenced through changes in...

Effect of temperature and surfactant on the control release of the microencapsu...

The objective of our work has been the microencapsulation of dyes with lecithin from soybean, with the formation of liposomes, as a substitute for synthetic auxiliaries so as to improve the quality of the effluent. Current scenarios promote the disintegration and leakage of the liposomes, such as, changes in temperature, pH and the use of surfactants. Since dyeing process is a mix of all these parameters, we pr...

Microencapsulation of acid dyes in liposomic structures of lecithin and surfact...