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Restraints to Anticoagulation Prescription in Atrial Fibrillation and Attitude ...

Introduction and Objectives: To evaluate the prescription rate of oral anticoagulants in atrial fibrillation, the factors associated with non-prescription, the reasons referred by the physicians for not prescribing anticoagulants including the new generation anticoagulants, and to perform a medium term follow-up assessment. Materials and Methods: Prospective study on consecutive patients with atrial fibrillatio...

The mitochondrial genome of the pinewood nematode (Bursaphelenchus xylophilus) ...

The pinewood nematode (PWN) Bursaphelenchus xylophilus is the causative agent of pine wilt disease and the greatest biological threat to conifer forests worldwide. Here we describe the near-complete mitochondrial DNA (mtDNA) sequence (12,945 bp) of the PWN lineage recently introduced in Europe. The absence of polymorphisms across the mtDNA of three Portuguese isolates suggests that a single mitochondrial lineag...

Complex III deficiency in a Portuguese family: expanding the clinical phenotype

A novel automatic algorithm for the segmentation of the lumen of the carotid ar...

A novel algorithm is proposed for the segmentation of the lumen and bifurcation boundaries of the carotid artery in B-mode ultrasound images. It uses the image contrast characteristics of the lumen and bifurcation of the carotid artery in relation to other tissues and structures for their identification. The relevant ultrasound data regarding the artery presented in the input image is identified using morpholog...

Automatic segmentation of the carotid artery in ultrasound B-mode images

B-mode ultrasound imaging is well-known and used in the medical imaging field; however, it presents various difficulties, specifically in tasks of image segmentation and surface reconstruction, due to intrinsic adverse characteristics, such like low contrast and noise [1,2]. Despite this, B-mode ultrasound imaging has been used in the diagnosis of several cardiac diseases, particularly, carotid artery diseases ...

Identification of a novel TTC19 mutation in a Portuguese family with complex II...

Publicado em: Livro de abstracts do congresso UMDF - 2012 ; Defects of mitochondrial complex III (CIII) are a relatively rare cause of mitochondrial dysfunction. CIII or ubiquinol-cytochrome c reductase is the third component of the mitochondrial respiratory chain and catalyzes the electrons transfer from reduced coenzyme Q to cytochrome c and is composed of 11 subunits; one encoded by mitochondrial DNA (MT-CY...

Autosomal Recessive Cerebellar Ataxia and Low Mitocondrial Complex III in a Por...

Publicado em: Livro de abstracts do congresso LIMPE_DISMOV 2012 ; Introduction: Defects of mitochondrial complex III (CIII) are a relatively rare cause of mitochondrial dysfunction. The complex catalyzes the electron transfer from reduced coenzyme Q to cytochrome c and is composed of 11 subunits, one of which (MT-CYB) is mtDNA encoded. Mutations in MT-CYB and in assembly factor BCS1L account for the vast major...

Ancestral origin of the ATTCT repeat expansion in spinocerebellar ataxia type 1...

Spinocerebellar ataxia type 10 (SCA10) is an autosomal dominant neurodegenerative disease characterized by cerebellar ataxia and seizures. The disease is caused by a large ATTCT repeat expansion in the ATXN10 gene. The first families reported with SCA10 were of Mexican origin, but the disease was soon after described in Brazilian families of mixed Portuguese and Amerindian ancestry. The origin of the SCA10 expa...

Os Processos de Mediação de Ciência em Televisão: Efeitos sobre a sua eficácia ...

The communication of scientific subjects is more than the process of “supplying” citizens with information; therefore, this communication raises several issues that exceed the mere transmission of knowledge, such as the perception of science in the current world, the role played by the scientist in thesociety, the consequences of the scientific and technological development and opinion-mak...

Molecular characterization of portuguese patients with Citrullinemia Type I (ur...