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Design and optimization of new simulated moving bed plants

The simulated moving bed (SMB) technology has attracted considerable attention for its efficiency as a chromatographic adsorptive separation. It has been increasingly applied to the separation of binary mixtures with low separation factors, namely to separate isomers. Although quite a vast amount of information has been published concerning the simulation and design of operating conditions of existing SMB plant...

Fractionation of multicomponent sugar mixtures using a pseudo simulated moving bed

A model for the fractionation of a ternary mixture of sugars by pseudo-simulated moving bed chromatography, according to the JO process of Japan Organo Co., is presented. This methodology is applied to the separation of a ternary mixture constituted by two sugars – sucrose (disaccharide) and fructose (monosaccharide) – and one non-sugar – betaine.

SMB chromatography applied to the separation/purification of fructose from cash...

The simulated moving-bed (SMB) technology has been successfully used in separations in petrochemical, food and fine chemical industries. This work is intended to show a potencial economic alternative for the industrial processing of the cashew apple juice. The cashew tree is a native tropical plant abundant in Northeastern Brazil, whose commercial value relies mainly on the processing of its nut. The penduncle ...

The concept of separation volume for the design of SMB processes

Enantiomers separation by simulated moving bed chromatography. Non-instantaneou...

The simulated moving bed (SMB) technology, first conceived for large bulk-scale separations in the petrochemical industry, has found increasingly new applications in the pharmaceutical industry. Among these, the separation of fine chemicals has been the subject of considerable study and research. This work presents the modeling, simulation and design of the operation of a SMB plant in order to separate a binary...