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Ethylazinphos Interaction with Membrane Lipid Organization Induces Increase of ...

Videira, Romeu A.; Antunes-Madeira, Maria C.; Madeira, Vítor M. C.

Ethylazinphos increases the passive proton permeability of lipid bilayers reconstituted with dipalmitoylphosphatidylcholine (DPPC) and mitochondrial lipids. A sharp increase of proton permeability is detected at insecticide/lipid molar ratios identical to those inducing phase separation in the plane of DPPC bilayers, as revealed by differential scanning calorimetry (DSC). Ethylazinphos progressively depresses t...


Changes induced by malathion, methylparathion and parathion on membrane lipid p...

Videira, Romeu A.; Antunes-Madeira, Maria C.; Lopes, Virgínia I. C. F.; Madeira, Vítor M. C.

Perturbations induced by malathion, methylparathion and parathion on the physicochemical properties of dipalmitoylphosphatidylcholine (DPPC) were studied by fluorescence anisotropy of DPH and DPH-PA and by differential scanning calorimetry (DSC). Methylparathion and parathion (50 [mu]M) increased the fluorescence anisotropy evaluated by DPH-PA and DPH, either in gel or in the fluid phase of DPPC bilayers, but m...


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