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Revisiting thyroid hormones in schizophrenia
Santos, Nadine Correia; Costa, Patrício Soares; Ruano, Dina; Macedo, António; Soares, Maria João; Valente, José; Pereira, Ana TelmaThyroid hormones are crucial during development and in the adult brain. Of interest, fluctuations in the levels of thyroid hormones at various times during development and throughout life can impact on psychiatric disease manifestation and response to treatment. Here we review research on thyroid function assessment in schizophrenia, relating interrelations between the pituitary-thyroid axis and major neurosign...
The BDI-II factor structure in pregnancy and postpartum: Two or three factors?
Carvalho Bos, Sandra; Pereira, Ana Telma; Marques, Mariana; Maia, Berta; Soares, Maria João; Valente, José; Gomes, Ana; Macedo, Antóniohttp://www.sciencedirect.com/science/article/B6VM1-4V57Y05-2/2/614a417822f6c536a126ed0b44ccc7f8
Perfectionism and sleep disturbance
Azevedo, Maria Helena Pinto de; Soares, Maria João; Bos, Sandra Carvalho; Gomes, Ana Allen; Maia, Berta; Marques, Mariana; Pereira, Ana TelmaThe main purpose of the present research was to explore gender-related associations between sleep disturbance and perfectionism dimensions in a large sample of undergraduate students. Perfectionism dimensions have been assessed using the Portuguese version of the Multidimensional Perfectionism Scale (Hewitt and Flett, 1991, J Pers Soc Psychol 60:456; Soares et al., 2003, Rev Port Psicossom 5:46) and sleep distu...
The Portuguese short form of the Eating Attitudes Test-40
Pereira, Ana Telma; Maia, Berta; Bos, Sandra; Soares, Maria João; Marques, Mariana; Macedo, António; Azevedo, Maria HelenaTo develop a Portuguese short form, the Eating Attitudes Test-40 (EAT-40) was administered to a community sample of 922 female students and to a clinical sample of 63 females suffering from an eating disorder. With the EAT responses of the community sample a factor analysis was performed and items with factor loadings ge 0.30 were selected. Internal consistency was computed for both the instrument and the facto...
Perfectionism and eating attitudes in Portuguese university students
Macedo, António; Soares, Maria João; Azevedo, Maria Helena; Gomes, Ana; Pereira, Ana Telma; Maia, Berta; Pato, MicheleThe main objective was to explore which are the dimensions of perfectionism that are linked to disordered eating behaviour (EB) in a large non-clinical sample of both genders.One thousand one hundred and sixty-three undergraduate students of the University of Coimbra completed the Portuguese versions of the multidimensional perfectionism scale (MPS) and the eating attitudes test (EAT-40).In both genders, the MP...
Association between schizophrenia and the syntaxin 1A gene
Wong, Albert H. C.; Trakalo, Joseph; Likhodi, Olga; Yusuf, Muneeb; Macedo, Antonio; Azevedo, Maria-Helena; Klempan, Tim; Pato, Michele T.Both microarray and candidate molecule studies have demonstrated that protein and mRNA expression of syntaxin and other genes involved in synaptic function are altered in the cerebral cortex of patients with schizophrenia.Methods ; http://www.sciencedirect.com/science/article/B6T4S-4CBVV0X-3/1/aaff2029f9c379930113bc4a5bb300cb
NR4A2 and schizophrenia: Lack of association in a Portuguese/Brazilian study
Ruano, Dina; Macedo, António; Dourado, Ana; Soares, Maria João; Valente, José; Coelho, Isabel; Santos, Vítor; Azevedo, Maria Helena; Goodman, AnnThe present study investigates the association of mutations in the nuclear receptor NR4A2 in schizophrenic patients. The human Nur-related receptor 1, NR4A2, is an orphan nuclear receptor that can be constitutively active as a transcription factor and for which no natural ligand has yet been identified. Alone or with retinoid X receptor, RXR, NR4A2 influences the expression of several genes important for human ...
NR4A2 and schizophrenia : lack of association in a portuguese/brazilian study
Ruano, Dina; Macedo, António; Dourado, Ana; Soares, Maria João; Valente, José; Coelho, Isabel; Santos, Vítor; Azevedo, Maria Helena; Goodman, AnnThe present study investigates the association of mutations in the nuclear receptor NR4A2 in schizophrenic patients. The human Nur-related receptor 1, NR4A2, is an orphan nuclear receptor that can be constitutively active as a transcription factor and for which no natural ligand has yet been identified. Alone or with retinoid X receptor, RXR, NR4A2 influences the expression of several genes important for human ...
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