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Novel 1-hydroxy-1,1-bisphosphonates derived from indazole: synthesis and charac...

Teixeira, Fátima C.; Antunes, Inês F.; Curto, M. João M.; Neves, M.; Teixeira, António P. S.

Bisphosphonates (BPs) are an important class of drugs used in the treatment of abnormal calcium metabolism diseases. The first syntheses of bisphosphonates derived from indazole, substituted at the N-1, N-2 and C-3 positions are reported. The 1-hydroxy-1,1-bisphosphonates were synthesized from the corresponding carboxylic acid or acyl chloride compounds, by two different methods. These BPs have a side chain wit...


Novel 1-hydroxy-1,1-bisphosphonates derived from indazole: synthesis and charac...

Teixeira, Fátima C.; Antunes, Inês F.; Curto, Maria João Marcelo; Neves, M.; Teixeira, António P. S.

Bisphosphonates (BPs) are an important class of drugs used in the treatment of abnormal calcium metabolism diseases. The first syntheses of bisphosphonates derived from indazole, substituted at the N-1, N-2 and C-3 positions are reported. The 1-hydroxy-1,1-bisphosphonates were synthesized from the corresponding carboxylic acid or acyl chloride compounds, by two different methods. These BPs have a side chain wit...

Data: 2009   |   Origem: Repositório do LNEG

New indazolebisphosphonates for bone targeted radiotherapy: synthesis, radiolab...

Neves, M.; Gano, L.; Teixeira, Fátima C.; Antunes, Inês F.; Santos, A.; Majkowska, A.; Bilewicz, A.

Data: 2008   |   Origem: Repositório do LNEG

New indazole and condensed pyrazole bisphosphonates

Teixeira, Fátima C.; Lucas, Carla; Antunes, Inês F.; Curto, Maria João Marcelo; Duarte, M. Teresa; André, Vânia

Data: 2008   |   Origem: Repositório do LNEG

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Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia