The tooth is an important sample in adverse forensic conditions. Its morphology and histology contributes for the preservation of the cellular components. ; http://www.sciencedirect.com/science/article/B8JHP-4SBRTWX-V/1/4edd71a84d252ef01f799c324b50a993
The main objective of this paper is to show that, despite some adverse forensic condition such as degraded human body remains and exhumed material, the dentine (in pulp dentine complex) keeps, in the majority of cases, its integrity. In this study, we use a sample of 30 human teeth (both with and without carious) after extraction during dental treatment. We analyze 15 STRs and both high-variable regions I and I...
Background: The Y chromosome has been used to compare the relationship between populations, representing a rich source of potential information to trace paternal lineages and providing a record of our relatedness. Among different population groups, African populations seem to be very interesting to study, considering the theory of the origin of modern humans and the ethnic variability usually existing. Methods:...
Background: The Y-chromosome polymorphisms have a great value to population genetic studies and evolutionary aspects since these markers show high levels of heterogeneity within and between populations, permitting the geographical distribution and ancestry of patrilineages to be evaluated. They complement the autosomal STRs and mtDNA matrilineage information. Y-linked STRs remain stable in given paternal lineag...
Background: The non-recombining portion of the Y chromosome represents a valuable tool for the study of human population history. The haploid, non-crossing-over behaviour of Y chromosome gives potentials in many aspects resembling the maternally inherited mtDNA. The advantages for forensic casework are obvious. The haploid state makes mixture patterns much simpler; in female/male stain mixtures, pure male DNA p...
Background: The polymorphism of the two hypervariable segments (HVI and HVII) of the control region of mtDNA was analyzed in a population of 81 unrelated individuals from Central Portugal and 48 from the Azores Islands, using a fluorescent-based electrophoresis sequencing method. Methods: Sequences have been obtained with ABI PRISM0 Big Dye Terminator and dRhodamine Terminator Cycle Sequencing Ready Reaction Ki...
Face ao precoce envolvimento do aparelho respiratório na infecção HIV os autores pretenderam avaliar as eventuais perturbações exercidas pelo HIV no pulmão profundo ao longo desta afecção. Com esta finalidade estudaram-se 25 indivíduos (21 homens e 4 mulheres) com uma média de idades de 35.6±11.5 anos, dos quais dezoito eram fumadores e sete não fumadores (carga tabágica média de 20.0±6.7 maços/ano), distribuíd...
Face à possibilidade de o HIV atingir precocemente o pulmão profundo, os AA procuraram averiguar os desvios que ocorrem nas células inflamatórias e/ou imunocompetentes deste território orgânico na fase de latências clínica desta infecção. Com essa finalidade aplicaram o seguinte protocolo a 14 voluntários HIV1 positivos (11 homens e 3 mulheres), clinicamente assintomáticos (grau II da classificação CDC) e com u...
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