Abstract BACKGROUND: CD4+CD25+ regulatory T cells play an essential role in maintaining immune homeostasis and preventing autoimmunity. Therefore, defects in Treg development, maintenance or function have been associated with several human autoimmune diseases including Systemic Lupus Erythematosus (SLE), a systemic autoimmune disease characterized by loss of tolerance to nuclear components and significantly mor...
CD4+CD25+ regulatory T cells play an essential role in maintaining immune homeostasis and preventing autoimmunity. Therefore, defects in Treg development, maintenance or function have been associated with several human autoimmune diseases including Systemic Lupus Erythematosus (SLE), a systemic autoimmune disease characterized by loss of tolerance to nuclear components and significantly more frequent in females...
Background: CD4(+)CD25(+) regulatory T cells play an essential role in maintaining immune homeostasis and preventing autoimmunity. Therefore, defects in Treg development, maintenance or function have been associated with several human autoimmune diseases including Systemic Lupus Erythematosus (SLE), a systemic autoimmune disease characterized by loss of tolerance to nuclear components and significantly more fre...
Foi selecionada uma amostra aleatória (334 indivíduos) de todos os pacientes diagnosticados com câncer de estômago no período de 1980 a 1995 no Instituto Nacional do Câncer, Rio de Janeiro, sendo revisados seus dados histopatológicos. A concordância entre os diagnósticos prévios e atuais quanto à Classificação de Lauren foi considerada substancial (kappa= 0,65). Baseando-se nesta classificação, observou-se um d...
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