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Chemical ecology of echinoderms : impact of environment and diet in metabolomic...
Pereira, David M.; Andrade, Paula B.; Pires, R. A.; Reis, R. L.The phylum Echinodermata constitutes a successful and widespread group comprising Asteroidea, Ophiuroidea, Echinoidea, Holothuroidea and Crinodeia. Nowadays, marine organisms are being given a lot of attention in drug discovery pipelines. In these studies, sponges and nudibranchs are frequently addressed, however an increasing number of works focus their attention in echinoderms. Given the fact that many of the...
Do bioactive carotenoids contribute to the color of edible mushrooms?
Ribeiro, Bárbara; Pinho, Paula Guedes de; Andrade, Paula B.; Oliveira, Carla; Ferreira, António César Silva; Baptista, Paula; Valentão, PatríciaCarotenoids are biologically active phytochemicals present as micro-components in fruits and vegetables, being responsible for their yellow, orange and red colors. The chromatographic behavior and the UV absorption spectrum provided by HPLC-DAD analysis constitute the clues for their identification. Mushrooms are of increasing importance in modern nutrition and medicine, due to the presence of metabolites with ...
Relevant principal component analysis applied to the characterisation of Portug...
Martins, Rui C.; Lopes, Victor V.; Valentão, Patrícia; Carvalho, João C. M. F.; Isabel, Paulo; Amaral, Maria T.; Batista, Maria T.; Andrade, Paula B.The main purpose of this study was the characterisation of ‘Serra da Lousã’ heather honey by using novel statistical methodology, relevant principal component analysis, in order to assess the correlations between production year, locality and composition. Herein, we also report its chemical composition in terms of sugars, glycerol and ethanol, and physicochemical parameters. Sugars profiles from ‘Serra da Lousã...
Do cultivar, geographical location and crop season influence phenolic profile o...
Amaral, Joana S.; Valentão, Patrícia; Andrade, Paula B.; Martins, Rui C.; Seabra, Rosa M.Walnut leaves from nine different cultivars (Arco, Franquette, Hartley, Lara, Marbot, Mayette, Meylannaise, Parisienne and Rego) were studied for their phenolic compounds. Samples were harvested along three consecutive years, at two different geographical locations, in order to evaluate if significant differences in the phenolics composition can be related with genetic, climatic or geographical factors. Nine co...
Water and methanolic extracts of Salvia officinalis protect HepG2 cells from t-...
Lima, Cristóvão F.; Valentão, Patrícia; Andrade, Paula B.; Seabra, Rosa M.; Ferreira, Manuel Fernandes; Wilson, Cristina PereiraCommon sage (Salvia officinalis L., Lamiaceae) is an aromatic and medicinal plant well known for its antioxidant properties. Some in vivo studies have shown the biological antioxidant effects of sage. However, the intracellular antioxidant mechanisms of action are still poorly understood. In this study, we evaluated the cytoprotective effects of two sage extracts (a water and a methanolic extract) against tert-...
The drinking of a Salvia officinalis infusion improves liver antioxidant status...
Lima, Cristóvão F.; Andrade, Paula B.; Seabra, Rosa M.; Ferreira, Manuel Fernandes; Wilson, Cristina PereiraIn this study we evaluate the biosafety and bioactivity (antioxidant potential) of a traditional water infusion (tea) of common sage (Salvia officinalis L.) in vivo in mice and rats by quantification of plasma transaminase activities and liver GST and GR enzyme activities. The replacement of water by sage tea for 14 days in the diet of rodents did not affect the body weight and food consumption and did not indu...
Xanthone biosynthesis and accumulation in calli and suspended cells of Hypericu...
Dias, Alberto Carlos Pires; Seabra, Rosa M.; Andrade, Paula B.; Ferreres, Federico; Ferreira, Manuel FernandesCalli and suspended cells of Hypericum androsaemum accumulated high levels of 1,3,5,6 and 1,3,6,7 oxygenated xanthones. The major compounds include simple oxygenated xanthones or derivatives with prenyl, pyran or methoxyl groups, four of them being new natural compounds. A hypothetical biosynthetic scheme is proposed based on the isolated compounds and statistical analysis. Xanthone accumulation was influenced ...
Physicochemical attributes and pollen spectrum of Portuguese heather honeys
Andrade, Paula B.; Amaral, M. Teresa; Isabel, Paulo; Carvalho, João C. M. F.; Seabra, Rosa M.; Cunha, António Proença daThe qualities of selected honey samples of "Serra da Lousã" (Portugal) from three consecutive harvests (20 samples from each harvest) were evaluated by determing the pollen spectrum and physicochemical attributes. The following determinations were carried out: moisture, electrical conductivity, hydroxymethylfurfural, diastase activity, pH, acidity (free, lactone and total), formol number, reducing sugars, appar...
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