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Cianose no pequeno lactente – desafio diagnóstico

Different Mechanisms of Apoptosis by Influenza A and B Virus

Background and Aims: The ability of Influenza A (infA) viruses to counteract and manipulate the host response to infection is well acknowledged. In addition, the activation of the PI3K/Akt survival pathway by the infA NS1 protein has been described as one of the strategies to delay the apoptotic response of the infected cell. As influenza B (infB) viruses differ genetically and phenotypically from infA viruses,...

Selective pressure acting on influenza virus neuraminidase protein and relation...

Neuraminidase (NA) protein of influenza viruses has the particularity of being under antibody and antiviral drug selective pressure, as it is one of the main surface antigens and the target of neuraminidase inhibitors(NAIs). The aim of this study is to investigate the selective pressure(SP) acting on the NA of seasonal and pandemic influenza viruses. It comprises two objectives: (a)to evaluate the contribution ...

Evaluation and Characterization of Influenza Antiviral Drug Resistance in Portu...

In 2007 started to be carried out for the first time in Portugal a study focused on influenza antiviral drug resistance. Three main objectives were established:(1)to determine the antiviral profile of influenza viruses to oseltamivir, zanamivir and amantadine;(2)to determine and monitor the baseline level of susceptibility along winter seasons and for each influenza sub(type);(3)to analyse and characterize the ...

Genomic Signatures and Antiviral Drug Susceptibility Profile of A(H1N1)pdm09

Background: Genetic changes in influenza surface and internal genes can alter viral fitness and virulence. Mutation trend analysis and antiviral drug susceptibility profiling of A(H1N1)pdm09 viruses is essential for risk assessment of emergent strains and disease management. Objective: To profile genomic signatures and antiviral drug resistance of A(H1N1)pdm09 viruses and to discuss the potential role of mutate...

Tamaño poblacional, uso del hábitat y relaciones interespecíficas de Agalychnis...

Entre los años 2006 y 2007, en un pequeño humedal de la localidad de San Francisco del Cabo al noroccidente de Ecuador, monitoreamos mensualmente una población de la rana arborícola Agalychnis spurrelli. Nuestros objetivos fueron: (1) determinar el tamaño poblacional y las fluctuaciones anuales de la población, (2) evaluar la distribución espacial el hábitat por categoría de edad; y (3) analizar las asociacione...

Manual de uso do GERELAB - Laboratório de Gerenciamento de Resíduos.

2010

High blood pressure in the pediatric age group

The definition of hypertension (HT) in the pediatric age group is based on the normal distribution of blood pressure (BP) in healthy children. Normal BP is defined as being below the 90th percentile for gender, age and height, and hypertension as equal to or higher than the 95th percentile on at least three separate occasions. If the values are above the 90th percentile but below the 95th percentile, the child ...

Outbreak of acute respiratory infection among infants in Lisbon, Portugal, caus...

Human adenoviruses (AdVs) typically cause mild illnesses in otherwise healthy hosts. We investigated a pediatric outbreak of acute respiratory infection with fatal outcomes that occurred in Lisbon, Portugal, in 2004. Biological specimens were collected from 83 children attending two nurseries, a kinesiotherapy clinic, and the household of a nanny. Adenovirus infection was confirmed in 48 children by PCR and vir...

Aortic deformities: not all are aneurysms