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Oncoplastic surgery of the breast – past, present and future

The breast conserving surgery has become the standard of care for early-stage breast cancer. The primary goal of this approach is the complete removal of the cancer with adequate surgical margins while preserving the natural shape and appearance of the breast. Poor cosmetic outcomes were still observed in up to 40% of patients. To solve this problem, specialized approaches to resection with con- comitant recons...

Métodos Preditivos de Metastização Ganglionar Adicional em Cancro da Mama com G...

Objectivos As recomendações para a realização de linfadenectomia axilar nos doentes com cancro da mama em estádio precoce e sujeitas a biópsia de gânglio sentinela com presença de macrometástase foram recentemente actualizadas, baseadas nos últimos estudos publicados (Z0011 e IBCSG 23-01). Mantém-se, no entanto, alguma controvérsia na decisão de não realização de cirurgia radical axilar nos doentes com gânglio ...

O raro é raro, mas existe...

An 11-year-old boy with pharyngitis and cough: Lemierre syndrome

The authors present the case of an 11-year-old boy with pharyngitis, treated with amoxicillin, that worsened on day 7, with cough, high fever and refusal to eat. Lethargy and respiratory distress were noted. Based on radiographic findings of bilateral infiltrates he was diagnosed with pneumonia and started on intravenous ampicillin and erythromycin. Two days later he complained of right-sided neck pain and a pa...

Carcinoma Oculto da Mama com Metástases Axilares. A Propósito de Dois Casos Clí...

INTRODUÇÃO: O carcinoma oculto é uma entidade pouco frequente, que se define como a presença de metástases com tumor primário indetetável na altura da apresentação. O prognóstico da maioria dos casos de tumor oculto é reservado, no entanto, o desenvolvimento de técnicas imunohistoquímicas que permitem a caracterização do tumor, tornaram alguns subgrupos de tumor oculto potencialmente curáveis. A presença de a...

Characterization of microinjection moulded composites of polyamide 6 and carbon...

Microinjection molding is a powerful technology in micro-manufacture, providing millimeter scale parts at large scale production rate. In order to produce homogeneous composite parts, good dispersion of the nanoreinforcement in the polymer matrix is required. In the present work the carbon nanotube (CNT) reinforcement was dispersed in polyamide 6 (PA6) using a mini twin-screw extruder. Nanocomposites were prepa...

Tackling the cell wall of the grape berry

Abstract: The cell wall (CW) is the dynamic border of plant cells. In grape berries, the CW decisively accounts for the difference between the pulp and skin cells, with direct consequences on the grape characteristics, wine quality and wine-making methods. The softening of mature berries results from the depolymerisation and solubilisation of CW polymers. Modifications of grape pulp and skin CW provide the flex...

An Enhanced Method for Vitis vinifera L. DNA Extraction from Wines

Cationic solid lipid nanoparticles (cSLN): Structure, stability and DNA binding...

Differential mesenteric fat deposition in bovines fed on silage or concentrate ...

© The Animal Consortium 2011 ; In the meat industry, the manipulation of fat deposition in cattle is of pivotal importance to improve production efficiency, carcass composition and ultimately meat quality. There is an increasing interest in the identification of key factors and molecular mechanisms responsible for the development of specific fat depots. This study aimed at elucidating the influence of breed an...