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Nanoencapsulation of bovine lactoferrin for food and biopharmaceutical applicat...
Balcão, V. M.; Costa, Carla Isabel; Matos, Carla M.; Moutinho, C.; Amorim, Manuela; Pintado, Manuela E.; Gomes, Ana P.; Vila, Marta M.; Teixeira, J. A.Lactoferrin has for long captured the interest of many researchers as a natural compound with a wide variety of uses. Lactoferrin is a monomeric, iron-binding 80 kDa glycoprotein, and appears to be the subfraction of whey with the best documented antiviral, antimicrobial, anticancer and immune modulating/enhancing effects. It belongs to the family of transferrin proteins, and serves to control iron levels in bo...
Novel whey-derived peptides with inhibitory effect against angiotensin-converti...
Tavares, Tânia; Del Mar Contreras, Maria; Amorim, Manuela; Pintado, Manuela; Recio, Esidra; Malcata, F. XavierWhey protein concentrate (WPC) was subjected to enzymatic hydrolysis by proteases from the flowers of Cynara cardunculus, and the resulting angiotensin-converting enzyme (ACE)-inhibitory effect was monitored. The whole WPC hydrolysate exhibited an IC50 value of 52.9±2.9ºg/mL, whereas the associated peptide fraction with molecular weight below 3 kDa scored 23.6±1.1ºg/mL. The latter fraction was submitted to RP-H...
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