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Gastric leiomyoma and hyperplastic polyposis coli in a patient with multiple cu...

BACKGROUND: Cutaneous leiomyomatosis has been associated with multiple uterine myomas and, more recently, with germline heterozygous mutations of the FH gene and certain types of renal cancer. Despite the growing amount of knowledge concerning this genodermatosis, its clinical spectrum remains incompletely characterized. OBJECTIVE: We report the observation of a patient with multiple cutaneous and uterine leiom...

Rare cause of fever in a patient with ulcerative colitis

O Doente Cirrótico na Unidade de Cuidados Intensivos: Avaliação do Prognóstico

INTRODUÇÃO: Os doentes com cirrose hepática admitidos em Unidades de Cuidados Intensivos (UCI) têm um prognóstico particularmente reservado. O prognóstico destes doentes pode ser avaliado com scores gerais (SOFA, APACHE, SAPS) ou com scores específicos de cirrose hepática (MELD, Child-Pugh). OBJECTIVOS: Avaliar o valor prognóstico dos scores gerais (SOFA, APACHE e SAPS) e dos scores específicos de cirrose hepát...

CARD15 mutations and colorectal cancer in a South European country

PURPOSE: CARD15 mutations are associated with higher susceptibility to Crohn's disease (CD) and longstanding colonic CD increases the risk of developing colorectal cancer (CRC). The relation between these mutations and sporadic CRC remains controversial. The aim of this study was to assess whether germline and/or somatic CARD15 mutations are risk factors for sporadic CRC in Portugal and whether there are genoty...

CARD15 Mutations and Colorectal Cancer in a South European Country

Prognostic scores in a gastroenterology intensive care unit

BACKGROUND: Several prognostic systems have been developed and validated in general Intensive Care Units (ICUs). No assessment of these scores was performed in specialized Gastroenterology Intensive Care Units (GICUs). AIM: To assess the prognostic accuracy of Acute Physiology and Chronic Health Evaluation (APACHE) II, Simplified Acute Physiology Score (SAPS) II and Sequential Organ Failure Assessment (SOFA) s...

Glycogenic acanthosis of the esophagus: an unusually endoscopic appearance

A strange duodenal lesion

Interlaminar and intralaminar fracture characterization of composites under mod...

The interlaminar and intralaminar fracture of laminated composites under mode i loading was studied using the double cantilever beam test. the effect of bridging on the measured fracture energy was assessed by cutting fibres during crack propagation. the fracture energy was evaluated considering a pre-viously developed data reduction scheme based on the beam theory and crack equivalent concept. the model only r...

Megacólon Tóxico - Experiência de um Serviço de Gastrenterologia