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The implications of nitrogen on the fermentative growth extension of Saccharomy...
Candeias, Marta; Alves-Pereira, I; Ferreira, RuiThe peptone is used to provide nitrogen to Saccharomyces cerevisiae, which is an essential element for growth. In nature and in industrial musts, essential nutrients for yeast growth are available in complex and variable flux. Some of these compounds are herbicides, where some specific microorganisms are capable to mineralize or degrade into more basic and less harmful compounds to the environmental. The isopro...
Decline in glutathione peroxidase and cytoplasmic catalases by lindane may caus...
Pita, T; Alves-Pereira, I; Ferreira, RuiLindane or gamma 1α,2α,3β,4α,5α,6β-hexachlorocyclohexane is an organochlorine insecticide, persistent in soils and aquifers, lipophilic, chemically and biochemically inert that accumulates along the human food chain. It is commonly used on a wide variety of crops, in warehouses, in public health to control insect-borne diseases, and (with fungicides) as a seed treatment. Lindane is also presently used in lotion...
Antioxidant power of Malus domestica juice partially reverses the oxidative eff...
Agostinho, J; Ferreira, Rui; Alves-Pereira, IApple juices are described as potential inhibitors of oxidative stress preventing chronic disorders such as cancer and cardiovascular disease. Accordingly, the main intention of this study was to evaluate the influence of Golden Delicious apple juice, from Beira Alta, Portugal on cell proliferation of S. cerevisiae UE-ME3 exposed to oxidant, vanadium pentoxide. The results show that 2.0 mM vanadium pentoxide i...
Growth temperature determines titanium dioxide nanoparticles response by Saccha...
Capela-Pires, JM; Alves-Pereira, I; Ferreira, RuiThe environmental levels of titanium dioxide nanoparticles (TiO2-NP), a new material described as ROS generator, has increased in several regions of the earth due its massive industrial use. Thus, the main purpose of this work was to determine the influence of temperature on response to TiO2-NP by S. cerevisiae UE-ME3.The results show that cells grown at 28 ºC show dry weight, protein and glutathione contents h...
Glutathione reductase play a key role in the differential response of Saccharom...
Candeias, M; Alves-Pereira, I; Ferreira, RuiThe isoproturon is a systemic herbicide applied in pre- and post-emergence control of annual grasses and broad-leaved weeds in winter crops that block photosynthesis, being listed by European Union as special substance that threaten the earth surface. Probably, can generate reactive oxygen species blocking the respiratory chain and cause oxidative stress and cell death. So, the main purpose of this study was to...
Diuron determines Saccharomyces cerevisiae UE-ME3 survival at beginning of expo...
Tenda, H; Alves-Pereira, I; Ferreira, RuiThe diuron is an herbicide used on autumn-winter crops, due to its ability to block the chloroplast electron chain at level of photosystem II. Furthermore, diuron can also exert toxic effects on heterotrophic beings, blocking the respiratory chain and ROS generating. Despite the progressive suppression of diuron application by Directive 200/60/CE, groundwater contamination will still persist. Therefore the main...
Vanadium pentoxide - diferential survival of three different strains of Sacchar...
Conim, A; Ferreira, Rui; Alves-Pereira, IVanadium is a heavy metal present in the Earth’s crust whose utilization by the industry of steel, pesticides and paints has increased in the last years, contributing to increase of its environmental level, making it a pollutant. Several studies reveal that vanadium causes genotoxic and mutagenic effects, although may be beneficial for some organisms, exerting antitumor effects by activating the signaling pathw...
Differential growth inhibition of Saccharomyces cerevisiae UE-ME3 and BY4741 by...
Capela-Pires, J; Ferreira, Rui; Alves-Pereira, INanoparticles of titanium dioxide, widely used as pigments or cosmetics, are usually found in molecular size < 100 nm. Sometimes, their poor thermal stability and large surface area can be correlated with their reactivity to cause changes in gene expression that may be used as biomarkers of exposure and cytotoxicity. Although the nanomaterials may be useful in medicine, their exposition to air or ultraviolet ra...
Isoproturon increases Saccharomyces cerevisiae UE-ME3 proliferation, blocking N...
Candeias, M; Alves-Pereira, I; Ferreira, RuiThe isoproturon (IPU) is an herbicide used in Autumn-Winter crops that often persists in soils and aquifers at levels considered toxic by European legislation. In eukaryotic cells the IPU can generate ROS and consequently oxidative stress and it may be involved in triggering of serious illnesses like cancer. Accordingly, it is urgent to find microorganisms useful in bioremediation of this phenylurea. The aim of...
Lindane toxicity: can glutathione reductase and glucose-6P-dehydrogenase of Sa...
Pita, T; Alves-Pereira, I; Ferreira, RuiLindane is an organochlorine persistent insecticide, lipophilic, chemically and biochemically stable, detected in the atmosphere, groundwater, sediments and soil. The literature describes this compound as toxic and able to affect animal reproduction and development. The aim of this study was to evaluate the effects of lindane in the wild-type S. cerevisiae UE-ME3 of Alentejo, Portugal, a unicellular eukaryotic ...
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