Therapeutic options for patients suffering from the more severe forms of spondyloarthritis have been rather limited in the last decades. There is now accumulating evidence that antitumor necrosis factor therapy is highly effective in spondyloarthritis, especially in ankylosing spondylitis and psoriatic arthritis. Based on the data recently published on more than 500 patients with ankylosing spondylitis and psor...
In Amyand's hernia, the hernia sac contains the appendix. This can be normal and accidentally found during herniotomy or inflamed and present as acute scrotum, although the latter is less frequent. We present a case of a male infant with scrotal abscess resulting from Amyand's hernia, with appendicitis and periappendicular abscess.
The consecration, on the Portuguese Constitution, of the Autonomous Regions came in the area of educational administration to point an ideological rupture, perhaps also a cultural tradition, with the centralist State. Moreover, it may be said that this reality was equally bring to the organizational dimension of the State, as a whole, analyzed by a prism of Education governance, also a willand intention of a re...
The major goal for the present work is to evaluate a biomimetic Finite Element (FE) model of the Intervertebral Disc (IVD). Recent studies have emphasized the importance of an accurate biomechanical modeling of the IVD, which is a highly complex biphasic medium. A novel biphasic poroelastic model was implemented and coupled with Wilson’s model (2005) for biphasic osmotic swelling behavior. Numerical tests were ...
Bioconversion of recalcitrant biomass/waste into bulk chemicals or biofuels is often not feasible. By gasification of these materials, syngas (mainly composed of CO2, CO and H2) is generated and can be used for the production of high value compounds by thermochemical or biotechnological processes. Here, three thermophilic cultures enriched with syngas mixtures or pure CO (T-Syn, T-Syn-CO and T-CO) were studied....
Thermophilic (55 °C) anaerobic microbial communities were enriched with a synthetic syngas mixture (composed of CO, H2, and CO2) or with CO alone. Cultures T-Syn and T-CO were incubated and successively transferred with syngas (16 transfers) or CO (9 transfers), respectively, with increasing CO partial pressures from 0.09 to 0.88 bar. Culture T-Syn, after 4 successive transfers with syngas, was also incubated w...
O 1.º Seminário Raiano de Combate à Desertificação, realizado em Castelo Branco, em 20 e 21 de Janeiro de 2011, com o patrocínio dos Ministérios da Agricultura, do Desenvolvimento Rural e das Pescas de Portugal, do Ministério do Ambiente e do Meio Rural e Marinho de Espanha e do Conselheiro de Agricultura e Desenvolvimento Rural da Junta da Extremadura, focalizou-se nas problemáticas do Despovoamento e do Aband...
Group B Streptococcus (GBS) is the leading cause of meningitis in neonates. We have previously shown that plasminogen, once recruited to the GBS cell surface and converted into plasmin by host-derived activators, leads to an enhancement of bacterial virulence. Here, we investigated whether plasmin(ogen) bound at the GBS surface contributes to blood-brain barrier penetration and invasion of the central nervous s...
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