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Topoisomerase-II mediated DNA damage: role of BRCA1 and other chromatin structu...
Alves, Inês Teles, 1985-Tese de mestrado. Biologia (Biologia Molecular Humana). Universidade de Lisboa, Faculdade de Ciências, 2009 ; DNA topoisomerases are essential to the resolution of DNA topology during several metabolic processes such as transcription, replication and chromosome segregation. Topoisomerase II (TOP2) catalyzes the passage of one DNA double strand through another and that is the reason why this enzyme can (un)knot...
Data: 2009
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Origem: Repositório da Universidade de Lisboa
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