Pretende-se, com esta comunicação, dar a conhecer um projecto multidisciplinar cujos objectivos visam a reconstituição paleoambiental do Entre Douro e Minho, durante a segunda metade do Sub-boreal assim como perceber as diferentes modalidades de povoamento existentes durante esta fase fito-climática. É nossa intenção investigar a evolução climática e vegetal, os processos erosivos e a formação de solos, durante...
The induction of systemic (IgG) and mucosal (IgA) antibody responses against the colonization factor I antigen (CFA/I) of enterotoxigenic Escherichia coli (ETEC) was evaluated in mice primed with an intramuscularly delivered CFA/I-encoding DNA vaccine followed by two oral immunizations with a live recombinant Salmonella typhimurium vaccine strain expressing the ETEC antigen. The booster effect induced by the or...
Stimulation of the mammalian immune system by administration of plasmid DNA has been shown to be an important approach for vaccine development against several pathogens. In the present study we investigated the use of DNA vaccines to induce immune responses against an enteric bacterial pathogen, enterotoxigenic Escherichia coli (ETEC). Three plasmid vectors encoding colonization factor antigen I (CFA/I), an ETE...
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