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Evaluation of acute and subchronic toxicity of a non-anticoagulant, but antithr...
Almeida-Lima,Jailma; Dantas-Santos,Nednaldo; Gomes,Dayanne L.; Cordeiro,Sara L.; Sabry,Diego A.; Costa,Leandro S.; Freitas,Maria de L.Fucan is a term used to denominate a family of sulfated polysaccharides rich in L-fucose. The brown alga Spatoglossum schröederi, Dictyotaceae, synthesizes three heterofucans named A, B, and C. Fucan A is a non-anticoagulant heterofucan which possesses potent antithrombotic (in vivo) and antiproliferative (in vitro) activities. However, its toxicity in vivo has not been determined. The present study examined th...
BC nanofibres : in vitro study of genotoxicity and cell proliferation
Moreira, Susana; Silva, Naisandra Bezerra; Almeida-Lima, Jailma; Rocha, Hugo Alexandre Oliveira; Medeiros, Silvia Regina BatistuzzoNanomaterials have unusual properties not found in the bulk materials, which can be exploited in numerous applications such as biosensing, electronics, scaffolds for tissue engineering, diagnostics and drug delivery. However, research in the past few years has turned up a range of potential health hazards, which has given birth to the new discipline of nanotoxicology. Bacterial cellulose (BC) is a promising mat...
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