Encontrados 17 documentos, a visualizar página 1 de 2
II Ciclo de Conferências : Conselho Técnico-Científico: temas atuais em investi...
Monteiro, M.C.H. ed.; Nunes, L.F.; Luz, J.P.; Silva, M.C.A.; Alegria, C.M.M.; Antunes, I.M.H.R.; Albuquerque, M.T.D.; Oliveira, S.F.; Almeida, L.M.A obra é constituída pelos resumos da comunicações apresentadas pelos docentes da Escola Superior Agrária do Instituto Politécnico de Castelo Branco e são referentes aos projetos de investigação nos quais estão envolvidos. ; O atual Conselho Técnico-Científico (CTC) da Escola Superior Agrária de Castelo Branco (ESACB) tomou posse em fevereiro de 2012, tendo decidido dar continuidade ao ciclo de conferências in...
Churg-Strauss syndrome: a disabling disease.
André, M C; Fraga, A; Reis, M Duarte; Filipe, P; Soares de Almeida, L M; Marques Gomes, M AChurg-Strauss syndrome (CSS) is an infrequent vasculitis that affects small to medium-sized vessels. We describe a 51 year-old-female admitted to our inpatient unit with bullae on her right foot and forearm with pain, paresthesias and impotence of the foot. There was rapid clinical deterioration with lost of gait and peripheral eosinophilia. Histopathology showed many extravascular eosinophils. Bone marrow had ...
Cariótipos de acesso diplóide sexual (BRA-00274) e tetraplóide apomítico (BRA-0...
NIELEN, S.; ALMEIDA, L. M.; CARNEIRO, V. T. C.; ARAÚJO, A. C. G.2008
Clonagem de fragmentos de DNA de um baculovirus patogênico à lagarta-do-álamo.
ALMEIDA, L. M.; PINEDO, F. J. R.; CASTRO, M. E. B.2007
Surface energies of simple metals from slabs: Comparison of exchange-correlatio...
Fiolhais, Carlos; Almeida, L. M.Surface energies of some simple metals (Be, Al, Mg, Li, and Na) were calculated within density functional theory. Various approximations for the exchange and correlation were tested: local density approximation (LDA), generalized gradient approximations (GGA), and meta-generalized gradient approximation (MGGA). We used the Crystal98 code to calculate slabs with one to 10 layers using both all-electron and pseud...
Extraction of aluminium surface energies from slab calculations: perturbative a...
Fiolhais, Carlos; Almeida, L. M.; Henriques, C.Surface energies of aluminium ((1 1 1), (1 1 0) and (1 0 0)) were calculated in second-order perturbation theory based on the jellium model, and by full atomistic models using a Gaussian basis set, in the framework of density functional theory. In both cases, surface energies were extracted from slab calculations using the incremental method, which considers two slabs with consecutive numbers of layers (6 and 7...
Properties of simple metals beyond the local density approximation of density f...
Almeida, L. M.; Fiolhais, Carlos; Causà, M.We calculated lattice parameters, binding energies, bulk moduli, and phase stabilities of some simple metals: Li, Be, Na, Mg, and Al. Our ab initio all-electron calculations were done within the framework of density functional theory using the Crystal-98 program. The accuracy of different functionals for exchange and correlation energies that go beyond the local density approximation (LDA) was tested. The recen...
Surface and curvature energies from jellium spheres: Density functional hierarc...
Almeida, L. M.; Perdew, John P.; Fiolhais, CarlosWe consider spherical jellium clusters with up to 200 electrons as a testing ground for density functional approximations to the exchange-correlation energy of a many-electron ground state. As nearly-exact standards, we employ Hartree–Fock energies at the exchange-only level and the diffusion Monte Carlo (DMC) energies of Sottile and Ballone (2001) at the correlated level. The density functionals tested are the...
Hydroxytamoxifen interaction with human erythrocyte membrane and induction of p...
Cruz Silva, M. M.; Madeira, V. M. C.; Almeida, L. M.; Custódio, J. B. A.4-Hydroxytamoxifen (OHTAM) is the most active metabolite of the widely prescribed anticancer drug tamoxifen (TAM) used in breast cancer therapy. This work describes the effects of OHTAM on isolated human erythrocytes, using standardized test conditions, to check for a putative contribution to the TAM-induced hemolysis and to study basic mechanisms involved in the interaction of OHTAM with cell membranes. Incuba...
Mitochondrial permeability transition induced by the anticancer drug etoposide
Custódio, J. B. A.; Cardoso, C. M. P.; Madeira, V. M. C.; Almeida, L. M.Etoposide (VP-16) is widely used for the treatment of several forms of cancer. The cytotoxicity of VP-16 has been assigned to the induction of apoptotic cell death but the signaling pathway for VP-16-induced apoptosis is essentially unknown. There is some evidence that this process depends on events associated with the loss of mitochondrial membrane potential ([Delta][Psi]) and/or release of apoptogenic factors...
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