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Evidence that the degree of band 3 phosphorylation modulates human erythrocytes...
Almeida, J. P. Lopes de; Freitas-Santos, T.; Saldanha, C.© 2011 – IOS Press and the authors. All rights reserved ; Recent evidence has shown that plasma fibrinogen, a major cardiovascular risk factor, interacts with the erythrocyte membrane and acts to influence blood flow via erythrocyte nitric oxide (NO) modulation. In the present pioneer in-vitro study, whole blood samples were harvested from healthy subjects and aliquots were incubated in the absence (control a...
Erythrocyte as a link between basic and clinical research
Saldanha, C.; Almeida, J. P. Lopes de© 2011 – IOS Press and the authors ; We review the major hemorheological experimental studies that show the erythrocyte aggregation as a link between basic and clinical research. The results of the clinical cross-sectional and longitudinal studies presented here will highlight the possible association between erythrocyte aggregation and plasma fibrinogen. Basic studies conducted in vitro are also mentioned as ...
Dithiothreitol revisited in red cells : a new head for an old hat
Almeida, J. P. Lopes de; Saldanha, C.© 2010 – IOS Press and the authors. All rights reserved ; In the present article the authors make an approach over the applications of dithiothreitol (DTT) in its different clinicallaboratory, potential and up-to-date sources. Dithiothreitol is a chemical reagent with a wide actuation spectrum not only from a laboratorial view but also from a therapeutic standpoint, more clinical and practical. DTT (i) is freq...
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